PMID- 12038521
OWN - NLM
STAT- MEDLINE
DCOM- 20021113
LR  - 20191106
IS  - 0017-6559 (Print)
IS  - 0017-6559 (Linking)
VI  - 31
IP  - 4
DP  - 2002
TI  - Primary lymphoma of the central nervous system and HTLV-I infection.
PG  - 365-7
AB  - Only a few cases of AIDS-related primary lymphomas of the central nervous system 
      (CNS) show a T-cell phenotype. We have recently studied two intravenous drug 
      users with HIV infection who had primary CNS T-cell lymphomas. In both cases, the 
      enzyme immunoassay (EIA) for HTLV gave a positive result. In the first case, 
      study by western-blot (WB) and specific PCR confirmed the human T-cell 
      lymphotropic virus type I (HTLV-I) infection and serological study by EIA for 
      HTLV of his mother was negative. In the second case, analysis of ante-mortem 
      serum samples by two different WBs showed an indeterminate pattern suggestive of 
      HTLV-I infection, but adequate samples for PCR were not available. We speculate 
      about the possibility that the horizontal transmission of HTLV-I infection could 
      have facilitated the devepolment of a primary CNS T-cell lymphoma in these HIV 
      patients, although they cannot be strictly considered as ATLL cases.
FAU - Calderon, Enrique J
AU  - Calderon EJ
AD  - Department of Internal Medicine, Virgen del Rocio University Hospital, Seville, 
      Spain. sandube@cica.es
FAU - Japon, Miguel A
AU  - Japon MA
FAU - Chinchon, Isidoro
AU  - Chinchon I
FAU - Soriano, Vicente
AU  - Soriano V
FAU - Capote, Francisco J
AU  - Capote FJ
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Haematologia (Budap)
JT  - Haematologia
JID - 0130266
SB  - IM
MH  - Adult
MH  - Central Nervous System Neoplasms/*etiology
MH  - HIV Infections/complications
MH  - HTLV-I Infections/*complications
MH  - Humans
MH  - Lymphoma, T-Cell/*etiology
MH  - Male
MH  - Substance Abuse, Intravenous/complications
EDAT- 2002/06/01 10:00
MHDA- 2002/11/26 04:00
CRDT- 2002/06/01 10:00
PHST- 2002/06/01 10:00 [pubmed]
PHST- 2002/11/26 04:00 [medline]
PHST- 2002/06/01 10:00 [entrez]
AID - 10.1163/15685590160141404 [doi]
PST - ppublish
SO  - Haematologia (Budap). 2002;31(4):365-7. doi: 10.1163/15685590160141404.