PMID- 12041952
OWN - NLM
STAT- MEDLINE
DCOM- 20020726
LR  - 20151119
IS  - 1521-6942 (Print)
IS  - 1521-6942 (Linking)
VI  - 16
IP  - 2
DP  - 2002 Apr
TI  - Management of skin disease in patients with lupus erythematosus.
PG  - 245-64
AB  - Skin disease in patients with lupus erythematosus may be subdivided into two 
      broad categories - those represented by a 'specific' histopathology, the 
      interface dermatitis, and those with changes that are not specific to lupus 
      erythematosus, for example, vasculitis, mucin infiltration, etc. The specific 
      skin lesions that are most common are discoid lupus erythematosus (DLE) and 
      subacute cutaneous lupus erythematosus (SCLE). Evaluation will allow the treating 
      physician to assign a prognosis. Cutaneous lesions can generally be managed with 
      standard therapies. Patients with discoid LE and subacute cutaneous LE are 
      generally photosensitive, and therefore sunscreens, protective clothing and 
      behavioural alteration should be discussed with all patients. Topical 
      corticosteroids are a standard form of therapy, but 'newer' agents such as 
      retinoids, calcipotriene and tacrolimus might be effective. Antimalarial agents 
      are generally effective. Attempts to reduce or stop smoking may aid in the 
      control of cutaneous LE. The choice of alternative therapy is personal, and 
      discussions of the risks and benefits should be carefully documented.
CI  - Copyright 2002 Elsevier Science Ltd.
FAU - Callen, Jeffrey P
AU  - Callen JP
AD  - University of Louisville, School of Medicine, 310 East Broadway, KY 40202, USA.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Netherlands
TA  - Best Pract Res Clin Rheumatol
JT  - Best practice & research. Clinical rheumatology
JID - 101121149
SB  - IM
MH  - Adult
MH  - Female
MH  - Humans
MH  - Infant
MH  - Lupus Erythematosus, Systemic/*complications/pathology/*therapy
MH  - Male
MH  - Middle Aged
MH  - Practice Patterns, Physicians'
MH  - Skin Diseases/*etiology/pathology/*therapy
RF  - 52
EDAT- 2002/06/04 10:00
MHDA- 2002/07/27 10:01
CRDT- 2002/06/04 10:00
PHST- 2002/06/04 10:00 [pubmed]
PHST- 2002/07/27 10:01 [medline]
PHST- 2002/06/04 10:00 [entrez]
AID - S1521694201902244 [pii]
AID - 10.1053/berh.2001.0224 [doi]
PST - ppublish
SO  - Best Pract Res Clin Rheumatol. 2002 Apr;16(2):245-64. doi: 
      10.1053/berh.2001.0224.