PMID- 12050783
OWN - NLM
STAT- Publisher
LR  - 20191120
IS  - 0582-9879 (Print)
IS  - 0582-9879 (Linking)
VI  - 33
IP  - 3
DP  - 2001
TI  - Hypochlorite and Cu(2 ) Induced Oxidation of High Density Lipoprotein.
PG  - 262-268
AB  - In order to further study on the properties of oxidatively modified high density 
      lipoproteins(Ox-HDL), the effects of hypochlorite and Cu(2 ) on HDL oxidation in 
      vitro were investigated. The results showed that, as to LDL, HDL was also 
      oxidized by hypochlorite and Cu(2 ), causing the formation of thiobarbituric acid 
      substances (TBARS) and increase of negative charges on HDL particle surface. It 
      was also found that during the oxidation of hypochlorite, both apoAI and apoAII 
      were degraded into small fragments, the phosphatidylcholine(PC) hydrolyzed into 
      lysophosphatidylcholine (LPC) and the protein components of HDL formed carbonyls.
FAU - Fu, Qiang
AU  - Fu Q
AD  - Apolipoproteins Research Unit, Institute of Biochemistry and Molecular Biology, 
      West China University of Medical Sciences, Chengdu 610041, China. 
      fucarl@mail.sc.cninfo.net
FAU - Liu, Bing-Wen
AU  - Liu BW
LA  - eng
PT  - Journal Article
PL  - China
TA  - Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai)
JT  - Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica
JID - 20730160R
EDAT- 2002/06/07 10:00
MHDA- 2002/06/07 10:00
CRDT- 2002/06/07 10:00
PHST- 2002/06/07 10:00 [pubmed]
PHST- 2002/06/07 10:00 [medline]
PHST- 2002/06/07 10:00 [entrez]
PST - ppublish
SO  - Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2001;33(3):262-268.