PMID- 12050860
OWN - NLM
STAT- MEDLINE
DCOM- 20030117
LR  - 20191106
IS  - 1473-7159 (Print)
IS  - 1473-7159 (Linking)
VI  - 2
IP  - 3
DP  - 2002 May
TI  - FISH banding methods: applications in research and diagnostics.
PG  - 217-25
AB  - Recently, several chromosome banding techniques based on fluorescence in situ 
      hybridization (FISH) have been developed for the human and the mouse genome. In 
      contrast to the standard chromosome banding techniques presently used, giving a 
      protein-related banding pattern, those FISH techniques are DNA-specific. 
      Currently the FISH banding methods are still under development and no high 
      resolution banding technique is available that can be used for a whole genome in 
      one hybridization. Nevertheless, FISH banding methods were used successfully for 
      research in evolution- and radiation-biology, as well as for studies on the 
      nuclear architecture. Moreover, their suitability for diagnostic purposes has 
      been proven in prenatal, postnatal and tumor cytogenetics, indicating that they 
      are an important tool with the potential to partly replace the conventional 
      banding techniques in future.
FAU - Liehr, Thomas
AU  - Liehr T
AD  - Institut fur Humangenetik und Anthropologie, D-07740 Jena, Germany. 
      I8lith@mti-n.mti.uni-jena.de
FAU - Heller, Anita
AU  - Heller A
FAU - Starke, Heike
AU  - Starke H
FAU - Claussen, Uwe
AU  - Claussen U
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - England
TA  - Expert Rev Mol Diagn
JT  - Expert review of molecular diagnostics
JID - 101120777
SB  - IM
MH  - Animals
MH  - Chromosome Banding/*methods/trends
MH  - Humans
MH  - In Situ Hybridization, Fluorescence/*methods/trends
MH  - Molecular Diagnostic Techniques/*methods/trends
RF  - 77
EDAT- 2002/06/08 10:00
MHDA- 2003/01/18 04:00
CRDT- 2002/06/08 10:00
PHST- 2002/06/08 10:00 [pubmed]
PHST- 2003/01/18 04:00 [medline]
PHST- 2002/06/08 10:00 [entrez]
AID - ERM020304 [pii]
AID - 10.1586/14737159.2.3.217 [doi]
PST - ppublish
SO  - Expert Rev Mol Diagn. 2002 May;2(3):217-25. doi: 10.1586/14737159.2.3.217.