PMID- 12056630
OWN - NLM
STAT- MEDLINE
DCOM- 20030109
LR  - 20161020
IS  - 0239-8508 (Print)
IS  - 0239-8508 (Linking)
VI  - 40
IP  - 2
DP  - 2002
TI  - Stages of the rat thymic medulla development in foetal period.
PG  - 171-2
AB  - Development of thymic medulla was examined on consecutive gestational days (GD) 
      in Wistar rats. Medullary thymic epithelial cells (TEC) were identified by 
      immunocytochemical localisation of neuron-specific enolase (NSE). Organisation of 
      thymic medullary architecture was determined by interaction of thymocytes with 
      NSE-positive TEC, that led to formation of lymphoepithelial complexes (GD 19), in 
      which the cells exhibited proliferative activity or traits of apoptosis. The 
      studies indicated that differentiation events and organisation of thymic medulla 
      require stage-specific interactions between TEC and thymocytes.
FAU - Brelinska, R
AU  - Brelinska R
AD  - Department of Histology and Embryology, University of Medical Sciences, Poznan, 
      Poland. rbrel@poczta.onet.pl
FAU - Ostalska, D
AU  - Ostalska D
FAU - Kaczmarek, E
AU  - Kaczmarek E
FAU - Kowalska, K
AU  - Kowalska K
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Poland
TA  - Folia Histochem Cytobiol
JT  - Folia histochemica et cytobiologica
JID - 8502651
RN  - 0 (Ki-67 Antigen)
RN  - EC 4.2.1.11 (Phosphopyruvate Hydratase)
SB  - IM
MH  - Animals
MH  - Apoptosis/physiology
MH  - Cell Division/physiology
MH  - Epithelial Cells/enzymology
MH  - Female
MH  - Gestational Age
MH  - In Situ Nick-End Labeling
MH  - Ki-67 Antigen/metabolism
MH  - Mitosis/physiology
MH  - Phosphopyruvate Hydratase/metabolism
MH  - Pregnancy
MH  - Rats
MH  - Rats, Wistar
MH  - Thymus Gland/cytology/*embryology/enzymology
EDAT- 2002/06/12 10:00
MHDA- 2003/01/10 04:00
CRDT- 2002/06/12 10:00
PHST- 2002/06/12 10:00 [pubmed]
PHST- 2003/01/10 04:00 [medline]
PHST- 2002/06/12 10:00 [entrez]
PST - ppublish
SO  - Folia Histochem Cytobiol. 2002;40(2):171-2.