PMID- 12057183
OWN - NLM
STAT- MEDLINE
DCOM- 20021010
LR  - 20190922
IS  - 0213-9111 (Print)
IS  - 0213-9111 (Linking)
VI  - 16
IP  - 3
DP  - 2002 May-Jun
TI  - [Concentrations of persistent toxic compounds in the Spanish population: a puzzle 
      without pieces and the protection of public health].
PG  - 257-66
AB  - The contamination by persistent toxic compounds (PTCs) of the general population 
      is a fact of relevance from a public health perspective. It is also relevant to 
      health care professionals, as well as for environmental, food, industrial and 
      economic policies. Though in Spain information on food contamination by PTCs 
      shows large time and geographic gaps, the scarcity of data is even more severe on 
      the concentrations that PTCs have in people: a representative study of a general 
      healthy population living in a wide geographic area has never been conducted in 
      the country. However, the available studies indicate that around 80-100% of the 
      population has detectable concentrations of DDE, PCBs, hexachlorbenzene or 
      lindane. Studies on the effects that PTCs have upon humans are extremely 
      infrequent in Spain. Yet, the international literature suggests that some PTCs 
      may induce significant biological and clinical effects at doses below those 
      traditionally deemed "safe". The mechanism of action of PTCs are not restricted 
      to endocrine disruption. Assessing the clinical and social relevance of the more 
      subtle and long-term effects of PTCs presents interesting challenges and 
      opportunities. Spain and other European countries lack population indicators on 
      the impact that environmental processes have on human health. Several government 
      levels have a role to fulfill in the monitoring of biological levels of PTCs 
      among persons in order to assess the risks of adverse health effects. Along with 
      over a hundred other countries. Spain will soon try to implement the Stockholm 
      treaty on persistent organic pollutants (POPs). This constitutes a new 
      opportunity to develop more efficient policies to control PTC residues in food, 
      humans and the environment. As part of the treaty implementation it is necessary 
      to launch a Report on factors that influence body concentrations of PTCs in the 
      Spain general population.
FAU - Porta, M
AU  - Porta M
AD  - Instituto Municipal de Investigacion Medica (IMIM), Universidad Autonoma de 
      Barcelona, Spain. mporta@imim.es
FAU - Kogevinas, M
AU  - Kogevinas M
FAU - Zumeta, E
AU  - Zumeta E
FAU - Sunyer, J
AU  - Sunyer J
FAU - Ribas-Fito, N
AU  - Ribas-Fito N
FAU - Ruiz, Laura
AU  - Ruiz L
FAU - Jariod, Manuel
AU  - Jariod M
FAU - Vioque, Jesus
AU  - Vioque J
FAU - Alguacil, Juan
AU  - Alguacil J
FAU - Martin, Piedad
AU  - Martin P
FAU - Malats, Nuria
AU  - Malats N
FAU - Ayude, Daniel
AU  - Ayude D
CN  - Grupo de Trabajo sobre Compuestos Toxicos Persistentes y Salud del IMIM
LA  - spa
PT  - English Abstract
PT  - Journal Article
PT  - Review
TT  - Concentraciones de compuestos toxicos persistentes en la poblacion espanola: el 
      rompecabezas sin piezas y la proteccion de la salud publica.
PL  - Spain
TA  - Gac Sanit
JT  - Gaceta sanitaria
JID - 8901623
RN  - 0 (Environmental Pollutants)
RN  - 0 (Pesticide Residues)
RN  - 0 (Xenobiotics)
SB  - IM
CIN - Gac Sanit. 2002 May-Jun;16(3):209-11. PMID: 12057174
MH  - Animals
MH  - Environmental Pollutants/adverse effects/*analysis
MH  - Europe
MH  - Food Contamination
MH  - Global Health
MH  - Humans
MH  - International Cooperation
MH  - Maximum Allowable Concentration
MH  - Pesticide Residues/analysis
MH  - Public Health
MH  - Spain
MH  - Time Factors
MH  - Tissue Distribution
MH  - Xenobiotics/adverse effects/*analysis
RF  - 61
EDAT- 2002/06/12 10:00
MHDA- 2002/10/11 04:00
CRDT- 2002/06/12 10:00
PHST- 2002/06/12 10:00 [pubmed]
PHST- 2002/10/11 04:00 [medline]
PHST- 2002/06/12 10:00 [entrez]
AID - 13032395 [pii]
AID - 10.1016/s0213-9111(02)71671-3 [doi]
PST - ppublish
SO  - Gac Sanit. 2002 May-Jun;16(3):257-66. doi: 10.1016/s0213-9111(02)71671-3.