PMID- 12073770
OWN - NLM
STAT- MEDLINE
DCOM- 20030103
LR  - 20041117
IS  - 0258-851X (Print)
IS  - 0258-851X (Linking)
VI  - 16
IP  - 2
DP  - 2002 Mar-Apr
TI  - A multi-resistant Acinetobacter baumannii outbreak in a general intensive care 
      unit.
PG  - 117-22
AB  - In an Intensive Care Unit, three patients were found infected and two colonized 
      with multiresistant Acinetobacter baumannii within a period of one week. To 
      identify the outbreak source, two surveillance studies were performed concerning 
      patients and the environment. Genotyping of isolates was performed by random 
      amplification of polymorphic DNA analysis (RAPD). Environmental sampling failed 
      to yield A. baumannii, with the exception of a single sample from a trunking. 
      RAPD-fingerprinting yielded identical patterns for all patient isolates including 
      the trunking isolate, thus confirming the suspected cluster. Since the strain 
      from the trunking had a susceptibility pattern and a RAPD pattern identical to 
      that of the strains isolated from the patients, we believe that this was the 
      likely source of the outbreak. In conclusion, A. baumannii outbreaks may be 
      quickly controlled by appropriate action of the hospital infection staff. 
      RAPD-fingerprinting may provide a useful and rapid identification technique for 
      the epidemiological investigation of a hospital outbreak.
FAU - Levidiotou, Stamatina
AU  - Levidiotou S
AD  - Microbiology Department, Medical School, University of Ioannina, POB 1186, 45, 
      110, Ioannina, Greece. sleveidi@cc.uoi.gr
FAU - Galanakis, Emmanouil
AU  - Galanakis E
FAU - Vrioni, Georgia
AU  - Vrioni G
FAU - Papamichael, Dimitrios
AU  - Papamichael D
FAU - Nakos, Georgios
AU  - Nakos G
FAU - Stefanou, Dimitrios
AU  - Stefanou D
LA  - eng
PT  - Journal Article
PL  - Greece
TA  - In Vivo
JT  - In vivo (Athens, Greece)
JID - 8806809
SB  - IM
MH  - Acinetobacter Infections/blood/drug therapy/*epidemiology
MH  - *Acinetobacter baumannii/isolation & purification
MH  - Aged
MH  - Cause of Death
MH  - Disease Outbreaks
MH  - Drug Resistance, Bacterial
MH  - *Drug Resistance, Multiple
MH  - Female
MH  - Greece
MH  - Hospitals, General
MH  - Humans
MH  - *Intensive Care Units
MH  - Male
MH  - Middle Aged
EDAT- 2002/06/21 10:00
MHDA- 2003/01/04 04:00
CRDT- 2002/06/21 10:00
PHST- 2002/06/21 10:00 [pubmed]
PHST- 2003/01/04 04:00 [medline]
PHST- 2002/06/21 10:00 [entrez]
PST - ppublish
SO  - In Vivo. 2002 Mar-Apr;16(2):117-22.