PMID- 12086214 OWN - NLM STAT- MEDLINE DCOM- 20020730 LR - 20191210 IS - 1525-2167 (Print) IS - 1532-2114 (Linking) VI - 1 IP - 2 DP - 2000 Jun TI - New digital measurement methods for left ventricular volume using real-time three-dimensional echocardiography: comparison with electromagnetic flow method and magnetic resonance imaging. PG - 96-104 AB - AIM: The aim of this study was to investigate the feasibility and accuracy of using symmetrically rotated apical long axis planes for the determination of left ventricular (LV) volumes with real-time three-dimensional echocardiography (3DE). METHODS AND RESULTS: Real-time 3DE was performed in six sheep during 24 haemodynamic conditions with electromagnetic flow measurements (EM), and in 29 patients with magnetic resonance imaging measurements (MRI). LV volumes were calculated by Simpson's rule with five 3DE methods (i.e. apical biplane, four-plane, six-plane, nine-plane (in which the angle between each long axis plane was 90 degrees, 45 degrees, 30 degrees or 20 degrees, respectively) and standard short axis views (SAX)). Real-time 3DE correlated well with EM for LV stroke volumes in animals (r=0.68-0.95) and with MRI for absolute volumes in patients (r-values=0.93-0.98). However, agreement between MRI and apical nine-plane, six-plane, and SAX methods in patients was better than those with apical four-plane and bi-plane methods (mean difference = -15, -18, -13, vs. -31 and -48 ml for end-diastolic volume, respectively, P<0.05). CONCLUSION: Apically rotated measurement methods of real-time 3DE correlated well with reference standards for calculating LV volumes. Balancing accuracy and required time for these LV volume measurements, the apical six-plane method is recommended for clinical use. FAU - Qin, J J AU - Qin JJ AD - The Cleveland Clinic Foundation, Ohio 44195, USA. FAU - Jones, M AU - Jones M FAU - Shiota, T AU - Shiota T FAU - Greenberg, N L AU - Greenberg NL FAU - Firstenberg, M S AU - Firstenberg MS FAU - Tsujino, H AU - Tsujino H FAU - Zetts, A D AU - Zetts AD FAU - Sun, J P AU - Sun JP FAU - Cardon, L A AU - Cardon LA FAU - Odabashian, J A AU - Odabashian JA FAU - Flamm, S D AU - Flamm SD FAU - White, R D AU - White RD FAU - Panza, J A AU - Panza JA FAU - Thomas, J D AU - Thomas JD LA - eng GR - R01 HL56688-01A1/HL/NHLBI NIH HHS/United States PT - Comparative Study PT - Evaluation Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, Non-P.H.S. PT - Research Support, U.S. Gov't, P.H.S. PL - England TA - Eur J Echocardiogr JT - European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology JID - 100890618 SB - IM CIN - Eur J Echocardiogr. 2000 Jun;1(2):84-6. PMID: 11916584 MH - Adult MH - Aged MH - Animals MH - Blood Flow Velocity MH - Computer Systems MH - Echocardiography, Three-Dimensional/*methods MH - Electromagnetic Phenomena MH - Feasibility Studies MH - Female MH - Humans MH - Image Processing, Computer-Assisted MH - Magnetic Resonance Imaging/*methods MH - Male MH - Middle Aged MH - Observer Variation MH - *Rheology MH - Sheep MH - Stroke Volume MH - Ventricular Function, Left/*physiology OTO - NASA OT - NASA Discipline Cardiopulmonary OT - NASA Program Biomedical Research and Countermeasures OT - Non-NASA Center FIR - Thomas, J D IR - Thomas JD IRAD- Cleveland Clinic Found, OH EDAT- 2002/06/28 10:00 MHDA- 2002/07/31 10:01 CRDT- 2002/06/28 10:00 PHST- 2002/06/28 10:00 [pubmed] PHST- 2002/07/31 10:01 [medline] PHST- 2002/06/28 10:00 [entrez] AID - S1525-2167(00)90016-7 [pii] AID - 10.1053/euje.2000.0016 [doi] PST - ppublish SO - Eur J Echocardiogr. 2000 Jun;1(2):96-104. doi: 10.1053/euje.2000.0016.