PMID- 12088214
OWN - NLM
STAT- MEDLINE
DCOM- 20020711
LR  - 20190513
IS  - 1079-5006 (Print)
IS  - 1079-5006 (Linking)
VI  - 56 Spec No 1
DP  - 2001 Mar
TI  - Physiologic effects of lowering caloric intake in nonhuman primates and nonobese 
      humans.
PG  - 66-75
AB  - Caloric restriction (CR) reduces the rate of aging and increases life span in all 
      small animal species studied to date, but the effects of CR in humans remain 
      uncertain. This review summarizes current knowledge of the effects of CR in 
      nonhuman primates and humans. The results suggest that CR has a range of 
      beneficial effects in nonhuman primates studied under laboratory conditions, and 
      short-term markers of CR seen in animal models appear to occur in humans subject 
      to CR also. However, the overall benefit of CR in human populations remains to be 
      established, and studies in human populations are needed.
FAU - Roberts, S B
AU  - Roberts SB
AD  - Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 
      Boston, Massachusetts 02111, USA. sroberts@hnrc.tufts.edu
FAU - Pi-Sunyer, X
AU  - Pi-Sunyer X
FAU - Kuller, L
AU  - Kuller L
FAU - Lane, M A
AU  - Lane MA
FAU - Ellison, P
AU  - Ellison P
FAU - Prior, J C
AU  - Prior JC
FAU - Shapses, S
AU  - Shapses S
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - J Gerontol A Biol Sci Med Sci
JT  - The journals of gerontology. Series A, Biological sciences and medical sciences
JID - 9502837
RN  - 0 (Lipids)
SB  - IM
MH  - Aging/physiology
MH  - Animals
MH  - Blood Pressure/physiology
MH  - Body Composition
MH  - Bone and Bones/physiology
MH  - *Energy Intake
MH  - Energy Metabolism
MH  - Humans
MH  - Lipids/blood
MH  - Primates/*physiology
MH  - Reference Values
MH  - Reproduction
RF  - 83
EDAT- 2002/06/29 10:00
MHDA- 2002/07/12 10:01
CRDT- 2002/06/29 10:00
PHST- 2002/06/29 10:00 [pubmed]
PHST- 2002/07/12 10:01 [medline]
PHST- 2002/06/29 10:00 [entrez]
AID - 10.1093/gerona/56.suppl_1.66 [doi]
PST - ppublish
SO  - J Gerontol A Biol Sci Med Sci. 2001 Mar;56 Spec No 1:66-75. doi: 
      10.1093/gerona/56.suppl_1.66.