PMID- 12112502
OWN - NLM
STAT- MEDLINE
DCOM- 20021004
LR  - 20071114
IS  - 1053-1807 (Print)
IS  - 1053-1807 (Linking)
VI  - 16
IP  - 1
DP  - 2002 Jul
TI  - Optimal post-contrast timing of breast MR image acquisition for architectural 
      feature analysis.
PG  - 42-50
AB  - PURPOSE: To define a post-contrast imaging time span during which diagnostic 
      accuracy of breast magnetic resonance (MR) architectural feature analysis is 
      maintained. MATERIALS AND METHODS: Seventy-five patients with 
      mammographically-visible or palpable findings underwent MR examination. Three 
      sequential post-contrast, fat-saturated, three-dimensional gradient-echo imaging 
      runs were acquired spanning 0-90, 90-180, and 180-270 seconds after contrast 
      injection. Five readers independently predicted the malignant potential of the MR 
      abnormalities. RESULTS: Receiver-operator characteristics (ROC) curves were our 
      primary measure of diagnostic accuracy. The accuracy of four readers was 
      unchanged over the three post-contrast runs. One reader was slightly more 
      accurate using the second and third runs than using the first. CONCLUSION: For 
      most readers, a single post-contrast run performed at any point during the first 
      four minutes and 30 seconds following injection should yield an equivalent 
      diagnostic accuracy. If any time period is less optimal, it is that of our first 
      run, performed between 0-90 seconds after contrast injection.
CI  - Copyright 2002 Wiley-Liss, Inc.
FAU - Nunes, Linda White
AU  - Nunes LW
AD  - MCP Hahnemann University, Hahnemann University Hospital, Department of Radiologic 
      Sciences, Philadelphia, Pennsylvania 19102, USA.
FAU - Englander, Sarah A
AU  - Englander SA
FAU - Charafeddine, Riad
AU  - Charafeddine R
FAU - Schnall, Mitchell D
AU  - Schnall MD
LA  - eng
GR  - P41-RR02305/RR/NCRR NIH HHS/United States
GR  - R01-CA58358/CA/NCI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - J Magn Reson Imaging
JT  - Journal of magnetic resonance imaging : JMRI
JID - 9105850
RN  - 0 (Contrast Media)
SB  - IM
MH  - Adult
MH  - Breast/*pathology
MH  - Breast Diseases/*diagnosis
MH  - Contrast Media
MH  - Female
MH  - Humans
MH  - Magnetic Resonance Imaging/*methods
MH  - Middle Aged
MH  - Prospective Studies
MH  - ROC Curve
MH  - Sensitivity and Specificity
MH  - Time Factors
EDAT- 2002/07/12 10:00
MHDA- 2002/10/09 04:00
CRDT- 2002/07/12 10:00
PHST- 2002/07/12 10:00 [pubmed]
PHST- 2002/10/09 04:00 [medline]
PHST- 2002/07/12 10:00 [entrez]
AID - 10.1002/jmri.10135 [doi]
PST - ppublish
SO  - J Magn Reson Imaging. 2002 Jul;16(1):42-50. doi: 10.1002/jmri.10135.