PMID- 12114764
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230315
IS  - 1559-0097 (Electronic)
IS  - 1046-3976 (Linking)
VI  - 10
IP  - 4
DP  - 1999 Winter
TI  - Origin and Genetic Background of Insulinomas.
PG  - 283-290
AB  - Insulin-producing B cell tumors (insulinomas) are the most frequent functioning 
      endocrine tumors of the pancreas. Available experimental evidence suggests that 
      the islet B cell is the most likely cell of origin of insulinomas, while the duct 
      endocrine cell should be considered if rearrangement of the pancreatic parenchyma 
      occurs. Data on the genetic background of insulinomas suggest that the B cell 
      tumor development may result from alteration of several genes, including the 
      multiple endocrine neoplasia type 1 (MEN1) gene.
FAU - Rindi, G
AU  - Rindi G
AD  - MD, PHD.
FAU - Candusso, M E
AU  - Candusso ME
FAU - Marchetti, A L
AU  - Marchetti AL
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Endocr Pathol
JT  - Endocrine pathology
JID - 9009288
EDAT- 2002/07/13 10:00
MHDA- 2002/07/13 10:01
CRDT- 2002/07/13 10:00
PHST- 2002/07/13 10:00 [pubmed]
PHST- 2002/07/13 10:01 [medline]
PHST- 2002/07/13 10:00 [entrez]
AID - EP1004283 [pii]
AID - 10.1007/BF02739770 [doi]
PST - ppublish
SO  - Endocr Pathol. 1999 Winter;10(4):283-290. doi: 10.1007/BF02739770.