PMID- 12119087 OWN - NLM STAT- MEDLINE DCOM- 20020812 LR - 20161124 IS - 0269-9052 (Print) IS - 0269-9052 (Linking) VI - 16 IP - 6 DP - 2002 Jun TI - Quantitive imaging in late traumatic brain injury. Part I: late imaging parameters in closed and penetrating head injuries. PG - 517-25 AB - OBJECTIVE: To ascertain the value of relatively simple quantitative radiologic measurements after head injury. Despite major advances in neuroradiology, analysis and reporting of imaging studies is based primarily on individual subjective and local experience, rather than on reproducible, standardized parameters; reliance on newer technologies can improve care, but also raises diagnostic costs. DESIGN: Blinded, retrospective, quantitative assessment of computerized tomography studies done some 14 years post-injury. OUTCOME MEASURES: Frontal horn width (FHW); septum-caudate distance (SCD); temporal horn width (THW); interuncal distance (IUD); third ventricle width (3VW); ventricular score (VS); sulcal width (SW); gray-white matter discriminability (GWMD) and subjective assessment of atrophy (SAOA). RESULTS: Diffuse and frontal damage was noted in both closed (CHI) and penetrating (PHI) head injury groups. Enlargement of frontal lobe parameters (septum caudate distance and frontal horn width suggest frontal injury in both closed and penetrating traumatic brain injury (TBI). Temporal horn width and inter-uncal distance were related to VS, 3VW and FHW in closed, but not in penetrating head injury. CONCLUSIONS: Simple linear CSF space measurements are correlated with volumetric and parenchymal measures, and can represent valuable and reliable low-cost quantitative measures of long term brain damage after TBI. FAU - Reider-Groswasser, Irith I AU - Reider-Groswasser II AD - Defense and Veterans Head Injury Program, Ra'anana, Israel. FAU - Groswasser, Zeev AU - Groswasser Z FAU - Ommaya, Alexander K AU - Ommaya AK FAU - Schwab, Karen AU - Schwab K FAU - Pridgen, Anthony AU - Pridgen A FAU - Brown, Herbert R AU - Brown HR FAU - Cole, Reginald AU - Cole R FAU - Salazar, Andres M AU - Salazar AM LA - eng PT - Clinical Trial PT - Journal Article PL - England TA - Brain Inj JT - Brain injury JID - 8710358 SB - IM MH - Atrophy MH - Brain/*diagnostic imaging/pathology MH - Cerebral Ventricles/pathology MH - Cerebral Ventriculography MH - Head Injuries, Closed/*diagnostic imaging/pathology MH - Head Injuries, Penetrating/*diagnostic imaging/pathology MH - Humans MH - Male MH - Tomography, X-Ray Computed EDAT- 2002/07/18 10:00 MHDA- 2002/08/13 10:01 CRDT- 2002/07/18 10:00 PHST- 2002/07/18 10:00 [pubmed] PHST- 2002/08/13 10:01 [medline] PHST- 2002/07/18 10:00 [entrez] AID - 10.1080/02699050110119141 [doi] PST - ppublish SO - Brain Inj. 2002 Jun;16(6):517-25. doi: 10.1080/02699050110119141.