PMID- 12119899
OWN - NLM
STAT- MEDLINE
DCOM- 20020930
LR  - 20061115
IS  - 1438-3276 (Print)
IS  - 1438-3276 (Linking)
VI  - 144
IP  - 23
DP  - 2002 Jun 6
TI  - [Respiratory manifestations of reflux disease. Gastric acidity--poison for 
      larynx, teeth and respiratory tract].
PG  - 26-30
AB  - Gastroesophageal reflux is now a generally accepted risk factor for the 
      development of adenocarcinoma of the esophagus. Less well known is the 
      relationship of reflux disease (GERD) and respiratory disorders. Among the 
      extra-esophageal manifestations of reflux disease is reflux laryngitis, which 
      affects up to 78 patients with chronic hoarseness, Reinke's edema, laryngeal 
      stricture, postnasal drip, asthma and non-cardiac chest pain. Despite popular 
      opinion, changes in lifestyle (for example, cessation of smoking and drinking, 
      avoidance of fatty foods) do not result in an improvement in symptoms. The 
      treatment of choice for GERD is the use of proton pump inhibitors (PPI) in the 
      form of stepdown therapy; in individual cases as symptom-orientated on-demand 
      therapy.
FAU - Issing, W J
AU  - Issing WJ
AD  - Klinik und Poliklinik fur Hals-, Nasen- und Ohrenkranke, Klinikum Grosshadern der 
      LMU Munchen. wolfgang.issing@web.de
FAU - Tauber, S
AU  - Tauber S
LA  - ger
PT  - English Abstract
PT  - Journal Article
TT  - Respiratorische Manifestationen der Refluxkrankheit. Der saure Magensaft--Gift 
      fur Kehlkopf, Zahne und Atemwege.
PL  - Germany
TA  - MMW Fortschr Med
JT  - MMW Fortschritte der Medizin
JID - 100893959
SB  - IM
MH  - Esophageal Neoplasms/*etiology
MH  - *Gastric Acidity Determination
MH  - Gastroesophageal Reflux/*complications
MH  - Humans
MH  - Laryngeal Diseases/*etiology
MH  - Respiratory Tract Diseases/*etiology
MH  - Risk Factors
MH  - Tooth Erosion/*etiology
EDAT- 2002/07/18 10:00
MHDA- 2002/10/02 04:00
CRDT- 2002/07/18 10:00
PHST- 2002/07/18 10:00 [pubmed]
PHST- 2002/10/02 04:00 [medline]
PHST- 2002/07/18 10:00 [entrez]
PST - ppublish
SO  - MMW Fortschr Med. 2002 Jun 6;144(23):26-30.