PMID- 12124561
OWN - NLM
STAT- MEDLINE
DCOM- 20021029
LR  - 20161026
IS  - 0021-9509 (Print)
IS  - 0021-9509 (Linking)
VI  - 43
IP  - 4
DP  - 2002 Aug
TI  - Low molecular weight heparins in the long-term treatment of venous 
      thromboembolism.
PG  - 495-500
AB  - Low molecular weight heparins (LMWHs) have extensively replaced unfractionated 
      heparin (UFH) in both thromboprophylaxis and initial treatment of venous 
      thromboembolism (VTE) and their use for such indications is now well established. 
      This paper reviews the role of LMWHs in the long-term treatment of VTE. Venous 
      thrombosis, although a very frequent occurrence in everyday practice, still 
      remains controversial in its treatment. Available literature comparing different 
      LMWHs with UFH and oral anticoagulants (OAs) is presented. Comparison and 
      evaluation of the effectiveness, safety and costs of alternative treatments are 
      also made. The differences of various LMWHs are discussed and the need for 
      separate clinical trials for every single LMWH is highlighted.
FAU - Liapis, C D
AU  - Liapis CD
AD  - 2nd Department of Propedeutic Surgery, Athens University Medical School, Laiko 
      Hospital, Greece.
FAU - Daskalopoulos, M E
AU  - Daskalopoulos ME
FAU - Daskalopoulou, S E
AU  - Daskalopoulou SE
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Italy
TA  - J Cardiovasc Surg (Torino)
JT  - The Journal of cardiovascular surgery
JID - 0066127
RN  - 0 (Anticoagulants)
RN  - 0 (Heparin, Low-Molecular-Weight)
RN  - 9005-49-6 (Heparin)
SB  - IM
MH  - Anticoagulants/therapeutic use
MH  - Heparin/therapeutic use
MH  - Heparin, Low-Molecular-Weight/*therapeutic use
MH  - Humans
MH  - Thromboembolism/*drug therapy
MH  - Time Factors
MH  - Venous Thrombosis/*drug therapy
RF  - 60
EDAT- 2002/07/19 10:00
MHDA- 2002/10/31 04:00
CRDT- 2002/07/19 10:00
PHST- 2002/07/19 10:00 [pubmed]
PHST- 2002/10/31 04:00 [medline]
PHST- 2002/07/19 10:00 [entrez]
PST - ppublish
SO  - J Cardiovasc Surg (Torino). 2002 Aug;43(4):495-500.