PMID- 12136654
OWN - NLM
STAT- MEDLINE
DCOM- 20020730
LR  - 20190822
IS  - 0387-5911 (Print)
IS  - 0387-5911 (Linking)
VI  - 76
IP  - 6
DP  - 2002 Jun
TI  - [Two cases of infectious mononucleosis-like syndrome associated with human 
      herpes-virus 6].
PG  - 455-9
AB  - We experienced two cases of infectious mononucleosis-like syndrome associated 
      with human herpesvirus 6 (HHV-6). One of the patients had been under medication 
      for depression and the other one for schizophrenia. Both of them were taking 
      carbamazepine for more than a week along with the other drugs. The manifestation 
      of the symptoms of those two were almost same, such as high fever, generalized 
      eruption, liver dysfunction, lymph-adenopathy, and existence of atypical 
      lymphocytes. Serological tests for EB virus, cytomegalovirus and herpes simplex 
      virus showed no significant change while the tests for HHV-6 showed increased 
      titers of IgG antibody during the courses. We also examined HHV-6 DNA by real 
      time quantitative PCR tests for HHV-6, and they appeared significantly high in 
      the peripheral blood samples.
FAU - Tomita, Shigehisa
AU  - Tomita S
AD  - Department of General Medicine, Juntendo University School of Medicine.
FAU - Takeda, Naoto
AU  - Takeda N
FAU - Isonuma, Hiroshi
AU  - Isonuma H
FAU - Sato, Tae
AU  - Sato T
FAU - Ohshima, Hiroko
AU  - Ohshima H
FAU - Ebe, Tsukasa
AU  - Ebe T
FAU - Sekiya, Sakae
AU  - Sekiya S
FAU - Matsumoto, Takao
AU  - Matsumoto T
FAU - Hayashida, Yasuo
AU  - Hayashida Y
FAU - Watanabe, Kazuyoshi
AU  - Watanabe K
LA  - jpn
PT  - Case Reports
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Kansenshogaku Zasshi
JT  - Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious 
      Diseases
JID - 0236671
RN  - 0 (Antibodies, Viral)
RN  - 0 (DNA, Viral)
SB  - IM
MH  - Adult
MH  - Antibodies, Viral/analysis
MH  - DNA, Viral/analysis
MH  - Depression/drug therapy
MH  - Female
MH  - *Herpesvirus 6, Human/immunology
MH  - Humans
MH  - Infectious Mononucleosis/etiology/*virology
MH  - Schizophrenia/drug therapy
EDAT- 2002/07/26 10:00
MHDA- 2002/07/31 10:01
CRDT- 2002/07/26 10:00
PHST- 2002/07/26 10:00 [pubmed]
PHST- 2002/07/31 10:01 [medline]
PHST- 2002/07/26 10:00 [entrez]
AID - 10.11150/kansenshogakuzasshi1970.76.455 [doi]
PST - ppublish
SO  - Kansenshogaku Zasshi. 2002 Jun;76(6):455-9. doi: 
      10.11150/kansenshogakuzasshi1970.76.455.