PMID- 12139506
OWN - NLM
STAT- MEDLINE
DCOM- 20030122
LR  - 20190916
IS  - 0268-9146 (Print)
IS  - 0268-9146 (Linking)
VI  - 33
IP  - 4
DP  - 2002 Aug
TI  - A high-resolution comparative RH map of the proximal part of bovine chromosome 1.
PG  - 271-9
AB  - Current comparative maps between human chromosome 21 and the proximal part of 
      cattle chromosome 1 are insufficient to define chromosomal rearrangements because 
      of the low density of mapped genes in the bovine genome. The recently completed 
      sequence of human chromosome 21 facilitates the detailed comparative analysis of 
      corresponding segments on BTA1. In this study eight bovine bacterial artificial 
      chromosome (BAC) clones containing bovine orthologues of human chromosome 21 
      genes, i.e. GRIK1, CLDN8, TIAM1, HUNK, SYNJ1, OLIG2, IL10RB, and KCNE2 were 
      physically assigned by fluorescence in situ hybridization (FISH) to 
      BTA1q12.1-q12.2. Sequence tagged site (STS) markers derived from these clones 
      were mapped on the 3000 rad Roslin/Cambridge bovine radiation hybrid (RH) panel. 
      In addition to these eight novel markers, 17 known markers from previously 
      published BTA1 linkage or RH maps were also mapped on the Roslin/Cambridge bovine 
      RH panel resulting in an integrated map with 25 markers of 355.4 cR(3000) length. 
      The human-cattle genome comparison revealed the existence of three chromosomal 
      breakpoints and two probable inversions in this region.
FAU - Drogemuller, C
AU  - Drogemuller C
AD  - Institute of Animal Breeding and Genetics, School of Veterinary Medicine 
      Hannover, Germany. cord.droegmueller@tiho-hannover.de
FAU - Bader, A
AU  - Bader A
FAU - Wohlke, A
AU  - Wohlke A
FAU - Kuiper, H
AU  - Kuiper H
FAU - Leeb, T
AU  - Leeb T
FAU - Distl, O
AU  - Distl O
LA  - eng
SI  - GENBANK/X05639
SI  - GENBANK/X98351
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Anim Genet
JT  - Animal genetics
JID - 8605704
RN  - 0 (DNA Primers)
RN  - 0 (Genetic Markers)
SB  - IM
MH  - Animals
MH  - Base Sequence
MH  - Cattle/*genetics
MH  - Chromosome Mapping/*veterinary
MH  - DNA Primers
MH  - Genetic Markers
MH  - Hybrid Cells/radiation effects
MH  - In Situ Hybridization, Fluorescence
MH  - Molecular Sequence Data
EDAT- 2002/07/26 10:00
MHDA- 2003/01/23 04:00
CRDT- 2002/07/26 10:00
PHST- 2002/07/26 10:00 [pubmed]
PHST- 2003/01/23 04:00 [medline]
PHST- 2002/07/26 10:00 [entrez]
AID - 866 [pii]
AID - 10.1046/j.1365-2052.2002.00866.x [doi]
PST - ppublish
SO  - Anim Genet. 2002 Aug;33(4):271-9. doi: 10.1046/j.1365-2052.2002.00866.x.