PMID- 12191500 OWN - NLM STAT- MEDLINE DCOM- 20030211 LR - 20190826 IS - 0169-328X (Print) IS - 0169-328X (Linking) VI - 102 IP - 1-2 DP - 2002 Jun 15 TI - Tool-use learning induces BDNF expression in a selective portion of monkey anterior parietal cortex. PG - 110-2 AB - Learning but not execution of tool-use induced expression of brain-derived neurotrophic factor (BDNF). The expression was highest in the anterior bank of the intraparietal sulcus, especially in the region posteriorly adjacent to the somatosensory shoulder and forearm region in area 3b, suggesting that BDNF plays a role in altering the body image of the hand to include the repeatedly used tool as its extension. FAU - Ishibashi, Hidetoshi AU - Ishibashi H AD - Section of Cognitive Neurobiology, Department of Maxillofacial Biology, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, 113-8549, Tokyo, Japan. ishibashi.cnb@tmd.ac.jp FAU - Hihara, Sayaka AU - Hihara S FAU - Takahashi, Mariko AU - Takahashi M FAU - Heike, Toshio AU - Heike T FAU - Yokota, Takashi AU - Yokota T FAU - Iriki, Atsushi AU - Iriki A LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Netherlands TA - Brain Res Mol Brain Res JT - Brain research. Molecular brain research JID - 8908640 RN - 0 (Brain-Derived Neurotrophic Factor) RN - 0 (RNA, Messenger) SB - IM MH - Animals MH - Brain Mapping MH - Brain-Derived Neurotrophic Factor/*genetics MH - Hand/innervation/physiology MH - Learning/*physiology MH - Macaca MH - Motor Skills/*physiology MH - Neuronal Plasticity/physiology MH - Neurons/cytology/*metabolism MH - Parietal Lobe/cytology/*metabolism/physiology MH - RNA, Messenger/metabolism MH - Somatosensory Cortex/cytology/metabolism MH - Synaptic Transmission/physiology EDAT- 2002/08/23 10:00 MHDA- 2003/02/13 04:00 CRDT- 2002/08/23 10:00 PHST- 2002/08/23 10:00 [pubmed] PHST- 2003/02/13 04:00 [medline] PHST- 2002/08/23 10:00 [entrez] AID - S0169328X02002012 [pii] AID - 10.1016/s0169-328x(02)00201-2 [doi] PST - ppublish SO - Brain Res Mol Brain Res. 2002 Jun 15;102(1-2):110-2. doi: 10.1016/s0169-328x(02)00201-2.