PMID- 12196848
OWN - NLM
STAT- MEDLINE
DCOM- 20021028
LR  - 20191106
IS  - 1701-2163 (Print)
IS  - 1701-2163 (Linking)
VI  - 24
IP  - 7
DP  - 2002 Jul
TI  - Use of low molecular weight heparin in acute venous thromboembolic events in 
      pregnancy.
PG  - 568-71
AB  - OBJECTIVE: To compare the maternal and neonatal outcomes arising from the use of 
      low molecular weight heparin (LMWH) or unfractionated heparin (UFH) in the 
      treatment of acute venous thromboembolism (VTE) in pregnancy. STUDY DESIGN: A 
      retrospective review of the charts of all women treated for acute VTE in 
      pregnancy at the Ottawa Hospital from January 1990 to December 1999. RESULTS: 
      Twenty-three cases were identified, of which 11 were treated with LMWH and 12 
      with UFH. Maternal and fetal outcomes were similar between the two groups. 
      Hospital length of stay was shorter in the LMWH group. There was no difference in 
      delivery management between the two groups. There was minor bleeding in 2 women 
      in the UFH group and none in the LMWH group. There was one recurrent VTE during 
      treatment in each of the groups. CONCLUSION: There is no difference in 
      complication rate between LMWH and UFH in the treatment of acute VTE in 
      pregnancy.
FAU - Malcolm, Janine C
AU  - Malcolm JC
AD  - University of Ottawa, Ottawa, ON, Canada.
FAU - Keely, Erin J
AU  - Keely EJ
FAU - Karovitch, Alan J
AU  - Karovitch AJ
FAU - Wells, Philip S
AU  - Wells PS
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Netherlands
TA  - J Obstet Gynaecol Can
JT  - Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et 
      gynecologie du Canada : JOGC
JID - 101126664
RN  - 0 (Anticoagulants)
RN  - 0 (Heparin, Low-Molecular-Weight)
RN  - 9005-49-6 (Heparin)
SB  - IM
MH  - Acute Disease
MH  - Adolescent
MH  - Adult
MH  - Anticoagulants/pharmacology/*therapeutic use
MH  - Female
MH  - Heparin/pharmacology/*therapeutic use
MH  - Heparin, Low-Molecular-Weight/pharmacology/*therapeutic use
MH  - Humans
MH  - Infant, Newborn
MH  - Ontario/epidemiology
MH  - Pregnancy
MH  - Pregnancy Complications, Cardiovascular/*drug therapy
MH  - Pregnancy Outcome/*epidemiology
MH  - Retrospective Studies
MH  - Thromboembolism/*drug therapy
MH  - Treatment Outcome
MH  - Venous Thrombosis/*drug therapy
EDAT- 2002/08/28 10:00
MHDA- 2002/10/29 04:00
CRDT- 2002/08/28 10:00
PHST- 2002/08/28 10:00 [pubmed]
PHST- 2002/10/29 04:00 [medline]
PHST- 2002/08/28 10:00 [entrez]
AID - S1701-2163(16)31059-3 [pii]
AID - 10.1016/s1701-2163(16)31059-3 [doi]
PST - ppublish
SO  - J Obstet Gynaecol Can. 2002 Jul;24(7):568-71. doi: 10.1016/s1701-2163(16)31059-3.