PMID- 12197909
OWN - NLM
STAT- MEDLINE
DCOM- 20021125
LR  - 20191106
IS  - 1083-4389 (Print)
IS  - 1083-4389 (Linking)
VI  - 7 Suppl 1
DP  - 2002
TI  - Helicobacter pylori: the challenge in therapy.
PG  - 43-9
AB  - For the therapeutic management of Helicobacter pylori infection, the Maastricht 
      2-2000 Consensus Report have introduced the concept of the 'treatment package' 
      that considers first- and second-line eradication therapies together. According 
      to this consensus statement, the first-line therapy for H. pylori eradication is 
      a combination of the proton pump inhibitors (PPI) or ranitidine bismuth citrate 
      (RBC) and claritromycin plus either amoxicillin or metronidazole. The second-line 
      treatment is suggested to be PPI-quadruple therapy for a minimum of 7 days. If 
      bismuth compounds are not available, PPI-based triple therapy will have to be 
      used as a second-line treatment only after susceptibility testing. Since no 
      considerable progress has been made during the past year in treatment regimens, 
      there is still a need for new compounds that are specific for H. pylori, which 
      could constitute future therapies.
FAU - Bazzoli, Franco
AU  - Bazzoli F
AD  - 2nd Department of Internal Medicine and Gastroenterology, University of Bologna, 
      Italy. bazzoli@alma.unibo.it
FAU - Pozzato, Paolo
AU  - Pozzato P
FAU - Rokkas, Theodore
AU  - Rokkas T
LA  - eng
PT  - Journal Article
PT  - Review
PL  - England
TA  - Helicobacter
JT  - Helicobacter
JID - 9605411
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Anti-Ulcer Agents)
RN  - 0 (Macrolides)
RN  - 0 (Penicillins)
SB  - IM
MH  - Anti-Bacterial Agents/*therapeutic use
MH  - Anti-Ulcer Agents/therapeutic use
MH  - Drug Resistance, Bacterial
MH  - Drug Therapy, Combination
MH  - Helicobacter Infections/*drug therapy
MH  - *Helicobacter pylori
MH  - Humans
MH  - Macrolides
MH  - Penicillins/*therapeutic use
RF  - 51
EDAT- 2002/08/29 10:00
MHDA- 2002/11/26 04:00
CRDT- 2002/08/29 10:00
PHST- 2002/08/29 10:00 [pubmed]
PHST- 2002/11/26 04:00 [medline]
PHST- 2002/08/29 10:00 [entrez]
AID - 007 [pii]
AID - 10.1046/j.1523-5378.7.s1.7.x [doi]
PST - ppublish
SO  - Helicobacter. 2002;7 Suppl 1:43-9. doi: 10.1046/j.1523-5378.7.s1.7.x.