PMID- 12199428 OWN - NLM STAT- MEDLINE DCOM- 20020917 LR - 20190910 IS - 0355-3140 (Print) IS - 0355-3140 (Linking) VI - 28 IP - 4 DP - 2002 Aug TI - Occupational exposure to hairdressing chemicals and immunoglobulin E synthesis. PG - 264-9 AB - OBJECTIVE: This study assessed the effect of exposure to hairdressing chemicals on total and allergen-specific serum immunoglobulin E (IgE) in hairdressers. METHODS: The study was based on a questionnaire sent to 100 hairdressers (91% responding) and a reference group of 95 office workers (84% responding). The questionnaire sought information on allergy, respiratory symptoms during the past year, work conditions (exposure), and smoking habits. The hairdressers were divided into two groups, one of high exposure and another of low exposure. Total serum IgE and allergen-specific IgE towards the most prevalent airborne allergens were analyzed. RESULTS: The serum levels of total IgE were significantly higher among the highly exposed hairdressers than among the office workers. The prevalence of asthma-like respiratory symptoms during the past year was significantly higher among the highly exposed hairdressers than among the office workers. The total serum IgE level was significantly higher among the hairdressers than among the office workers (101 versus 51 IU/ml blood), but this difference disappeared after adjustment for age, atopy, and smoking. A total of 5.5% of the hairdressers versus none of the office workers had specific serum IgE antibodies towards latex. There were no differences in general allergy (Phadiatop) among the hairdressers and office workers. CONCLUSIONS: Serum levels of total IgE were significantly higher among highly exposed hairdressers than among office workers. The relationship could not be completely explained by such covariables as age, smoking, or sensitization to latex allergens. FAU - Hollund, Bjorg Eli AU - Hollund BE AD - Section for Occupational Medicine, University of Bergen, Norway. Bjorg.Hollund@isf.uib.no FAU - Moen, Bente E AU - Moen BE FAU - Egeland, Grace M AU - Egeland GM FAU - Florvaag, Erik AU - Florvaag E FAU - Omenaas, Ernst AU - Omenaas E LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Finland TA - Scand J Work Environ Health JT - Scandinavian journal of work, environment & health JID - 7511540 RN - 0 (Allergens) RN - 0 (Hair Preparations) RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Allergens/immunology MH - Asthma/chemically induced MH - *Beauty Culture MH - Hair Preparations/*adverse effects MH - Humans MH - Immunoglobulin E/*biosynthesis/immunology MH - Inhalation Exposure MH - Norway/epidemiology MH - Occupational Exposure/*adverse effects MH - Surveys and Questionnaires MH - Workforce EDAT- 2002/08/30 10:00 MHDA- 2002/09/18 10:01 CRDT- 2002/08/30 10:00 PHST- 2002/08/30 10:00 [pubmed] PHST- 2002/09/18 10:01 [medline] PHST- 2002/08/30 10:00 [entrez] AID - 674 [pii] AID - 10.5271/sjweh.674 [doi] PST - ppublish SO - Scand J Work Environ Health. 2002 Aug;28(4):264-9. doi: 10.5271/sjweh.674.