PMID- 12206518
OWN - NLM
STAT- MEDLINE
DCOM- 20021024
LR  - 20170214
IS  - 0954-4119 (Print)
IS  - 0954-4119 (Linking)
VI  - 216
IP  - 4
DP  - 2002
TI  - An in vitro study of the reduction in wear of metal-on-metal hip prostheses using 
      surface-engineered femoral heads.
PG  - 219-30
AB  - Although the wear of existing metal-on-metal (MOM) hip prostheses (1 mm3/10(6) 
      cycles) is much lower than the more widely used polyethylene-on-metal bearings, 
      there are concerns about the toxicity of metal wear particles and elevated metal 
      ion levels, both locally and systemically, in the human body. The aim of this 
      study was to investigate the possibility of reducing the volume of wear, the 
      concentration of metal debris and the level of metal ion release through using 
      surface-engineered femoral heads. Three thick (8-12 microm) coatings (TiN, CrN 
      and CrCN) and one thin (2 microm) coating (diamond-like carbon, DLC), were 
      evaluated on the femoral heads when articulating against high carbon content 
      cobalt-chromium alloy acetabular inserts (HC CoCrMo) and compared with a 
      clinically used MOM cobalt-chromium alloy bearing couple using a physiological 
      anatomical hip joint simulator (Leeds Mark II). This study showed that CrN, CrCN 
      and DLC coatings produced substantially lower wear volumes for both the coated 
      femoral heads and the HC CoCrMo inserts. The TiN coating itself had little wear, 
      but it caused relatively high wear of the HC CoCrMo inserts compared with the 
      other coatings. The majority of the wear debris for all half-coated couples 
      comprised small, 30 nm or less, CoCrMo metal particles. The Co, Cr and Mo ion 
      concentrations released from the bearing couples of CrN-, CrCN- and DLC-coated 
      heads articulating against HC CoCrMo inserts were at least 7 times lower than 
      those released from the clinical MOM prostheses. These surface-engineered femoral 
      heads articulating on HC CoCrMo acetabular inserts produced significantly lower 
      wear volumes and rates, and hence lower volumetric concentrations of wear 
      particles, compared with the clinical MOM prosthesis. The substantially lower ion 
      concentration released by these surface-engineered components provides important 
      evidence to support the clinical application of this technology.
FAU - Fisher, J
AU  - Fisher J
AD  - Medical and Biological Engineering Research Group, School of Mechanical 
      Engineering, University of Leeds, UK.
FAU - Hu, X Q
AU  - Hu XQ
FAU - Tipper, J L
AU  - Tipper JL
FAU - Stewart, T D
AU  - Stewart TD
FAU - Williams, S
AU  - Williams S
FAU - Stone, M H
AU  - Stone MH
FAU - Davies, C
AU  - Davies C
FAU - Hatto, P
AU  - Hatto P
FAU - Bolton, J
AU  - Bolton J
FAU - Riley, M
AU  - Riley M
FAU - Hardaker, C
AU  - Hardaker C
FAU - Isaac, G H
AU  - Isaac GH
FAU - Berry, G
AU  - Berry G
FAU - Ingham, E
AU  - Ingham E
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Proc Inst Mech Eng H
JT  - Proceedings of the Institution of Mechanical Engineers. Part H, Journal of 
      engineering in medicine
JID - 8908934
RN  - 0 (Chromium Alloys)
RN  - 0 (Coated Materials, Biocompatible)
RN  - 12035-60-8 (titanium nickelide)
RN  - 7440-44-0 (Carbon)
RN  - 7OV03QG267 (Nickel)
RN  - D1JT611TNE (Titanium)
SB  - IM
MH  - Carbon/chemistry
MH  - Chromium Alloys/chemistry
MH  - Coated Materials, Biocompatible/*chemistry
MH  - Equipment Failure Analysis/instrumentation/*methods
MH  - Friction
MH  - Hardness
MH  - Hardness Tests
MH  - *Hip Prosthesis
MH  - Materials Testing/instrumentation/*methods
MH  - Models, Biological
MH  - Nickel/chemistry
MH  - Prosthesis Design/*methods
MH  - Titanium/chemistry
EDAT- 2002/09/11 10:00
MHDA- 2002/10/31 04:00
CRDT- 2002/09/11 10:00
PHST- 2002/09/11 10:00 [pubmed]
PHST- 2002/10/31 04:00 [medline]
PHST- 2002/09/11 10:00 [entrez]
AID - 10.1243/09544110260138709 [doi]
PST - ppublish
SO  - Proc Inst Mech Eng H. 2002;216(4):219-30. doi: 10.1243/09544110260138709.