PMID- 12218741
OWN - NLM
STAT- MEDLINE
DCOM- 20021209
LR  - 20190901
IS  - 0195-9131 (Print)
IS  - 0195-9131 (Linking)
VI  - 34
IP  - 9
DP  - 2002 Sep
TI  - Symposium: Limits to fat oxidation by skeletal muscle during 
      exercise--introduction.
PG  - 1475-6
AB  - Lipids, in the form of adipose tissue triacylglycerol (TG), intramuscular 
      triglyceride (IMTG), and dietary-derived fatty acids (FA) from plasma TG 
      (chylomicrons), and very low-density lipoproteins (VLDL), represent the largest 
      store of nutrient energy in humans. Yet despite the abundance of endogenous TG, 
      there is limited capacity for FA oxidation during exercise: there are no 
      mechanisms that match the availability and metabolism of FA to the rate of energy 
      expenditure. Because of the body's limited carbohydrate (CHO) stores, and because 
      depletion of muscle and liver glycogen reserves often coincide with exhaustion, 
      there is interest in several nutritional interventions that increase FA 
      availability and rates of fat oxidation during exercise: such strategies have the 
      potential to slow the rate of glycogen utilization and delay the onset of 
      fatigue. The five papers comprising this symposium provide a synopsis of 1) the 
      regulation of fat oxidation in human skeletal muscle during aerobic exercise; 2) 
      selected nutritional techniques that increase fat oxidation, spare endogenous CHO 
      stores, and modify exercise capacity; and 3) dietary manipulations that alter 
      macronutrient availability and muscle gene expression.
FAU - Hawley, John A
AU  - Hawley JA
AD  - Exercise Metabolism Group, School of Medical Sciences, RMIT University, PO Box 
      71, Bundoora, Victoria 3083, Australia. john.hawley@rmit.edu.au
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Med Sci Sports Exerc
JT  - Medicine and science in sports and exercise
JID - 8005433
SB  - IM
MH  - Exercise/*physiology
MH  - Humans
MH  - *Lipid Metabolism
MH  - Muscle, Skeletal/*metabolism
MH  - Oxidation-Reduction
EDAT- 2002/09/10 10:00
MHDA- 2002/12/10 04:00
CRDT- 2002/09/10 10:00
PHST- 2002/09/10 10:00 [pubmed]
PHST- 2002/12/10 04:00 [medline]
PHST- 2002/09/10 10:00 [entrez]
AID - 10.1097/00005768-200209000-00012 [doi]
PST - ppublish
SO  - Med Sci Sports Exerc. 2002 Sep;34(9):1475-6. doi: 
      10.1097/00005768-200209000-00012.