PMID- 12230591
OWN - NLM
STAT- MEDLINE
DCOM- 20030211
LR  - 20220408
IS  - 0333-1024 (Print)
IS  - 0333-1024 (Linking)
VI  - 22
IP  - 7
DP  - 2002 Sep
TI  - Migraine: preventive treatment.
PG  - 491-512
AB  - Migraine is a common episodic headache disorder. A comprehensive headache 
      treatment plan includes acute attack treatment to relieve pain and impairment and 
      long-term preventive therapy to reduce attack frequency, severity, and duration. 
      Circumstances that might warrant preventive treatment include: (i) migraine that 
      significantly interferes with the patient's daily routine despite acute 
      treatment; (ii) failure, contraindication to, or troublesome side-effects from 
      acute medications; (iii) overuse of acute medications; (iv) special 
      circumstances, such as hemiplegic migraine; (v) very frequent headaches (more 
      than two a week); or (vi) patient preference. Start the drug at a low dose. Give 
      each treatment an adequate trial. Avoid interfering, overused, and 
      contraindicated drugs. Re-evaluate therapy. Be sure that a woman of childbearing 
      potential is aware of any potential risks. Involve patients in their care to 
      maximize compliance. Consider co-morbidity. Choose a drug based on its proven 
      efficacy, the patient's preferences and headache profile, the drug's 
      side-effects, and the presence or absence of coexisting or co-morbid disease. 
      Drugs that have documented high efficacy and mild to moderate adverse events 
      (AEs) include beta-blockers, amitriptyline, and divalproex. Drugs that have lower 
      documented efficacy and mild to moderate AEs include selective serotonin reuptake 
      inhibitors (SSRIs), calcium channel antagonists, gabapentin, topiramate, 
      riboflavin, and non-steroidal anti-inflammatory drugs.
FAU - Silberstein, S D
AU  - Silberstein SD
AD  - Jefferson Headache Center, and Thomas Jefferson University Hospital, 
      Philadelphia, PA 19107, USA. Stephen.Silberstein@mail.tju.ed
FAU - Goadsby, P J
AU  - Goadsby PJ
LA  - eng
PT  - Journal Article
PT  - Review
PL  - England
TA  - Cephalalgia
JT  - Cephalalgia : an international journal of headache
JID - 8200710
RN  - 0 (Analgesics)
SB  - IM
CIN - Cephalalgia. 2004 Oct;24(10):908; author reply 908-9. PMID: 15377326
MH  - Analgesics/therapeutic use
MH  - Clinical Trials as Topic/methods/statistics & numerical data
MH  - Humans
MH  - Migraine Disorders/drug therapy/*prevention & control
RF  - 282
EDAT- 2002/09/17 10:00
MHDA- 2003/02/13 04:00
CRDT- 2002/09/17 10:00
PHST- 2002/09/17 10:00 [pubmed]
PHST- 2003/02/13 04:00 [medline]
PHST- 2002/09/17 10:00 [entrez]
AID - 386 [pii]
AID - 10.1046/j.1468-2982.2002.00386.x [doi]
PST - ppublish
SO  - Cephalalgia. 2002 Sep;22(7):491-512. doi: 10.1046/j.1468-2982.2002.00386.x.