PMID- 12322803 OWN - NLM STAT- MEDLINE DCOM- 20030326 LR - 20190605 IS - 0918-2918 (Print) IS - 0918-2918 (Linking) VI - 41 IP - 9 DP - 2002 Sep TI - CD56 positive intestinal T-cell lymphoma: treatment with high dose chemotherapy and autologous peripheral blood stem cell transplantation. PG - 734-7 AB - A 63-year-old man presented with a perforation of the small intestine. A diagnosis of intestinal T-cell lymphoma (ITCL) was made from CD (cluster differentiation) 3 positivity and a rearrangement of T-cell receptor genes. The tumor also expressed CD56, which suggests it belongs to a rare subtype derived from activated cytotoxic intraepithelial T lymphocytes. Although the prognosis of ITCL has been considered to be very poor irrespective of CD56 positivity, complete remission was achieved in this case by high dose chemotherapy followed by autologous peripheral blood stem cell transplantation (auto-PBSCT) even after relapse. Auto-PBSCT in the earlier stage of the disease might improve the prognosis. FAU - Okuda, Mitsutaka AU - Okuda M AD - Department of Internal Medicine, Miyagi Cancer Center, Natori. FAU - Nomura, Jun AU - Nomura J FAU - Tateno, Hiroo AU - Tateno H FAU - Kameoka, Junichi AU - Kameoka J FAU - Sasaki, Takeshi AU - Sasaki T LA - eng PT - Case Reports PT - Journal Article PL - Japan TA - Intern Med JT - Internal medicine (Tokyo, Japan) JID - 9204241 RN - 0 (CD56 Antigen) SB - IM MH - Antineoplastic Combined Chemotherapy Protocols/*therapeutic use MH - CD56 Antigen/*metabolism MH - Combined Modality Therapy MH - Humans MH - Intestinal Neoplasms/metabolism/pathology/*therapy MH - Intestinal Perforation/diagnostic imaging/pathology/surgery MH - Lymphoma, T-Cell/metabolism/pathology/*therapy MH - Male MH - Middle Aged MH - Peripheral Blood Stem Cell Transplantation/*methods MH - Remission Induction/methods MH - Tomography, X-Ray Computed MH - Transplantation, Autologous MH - Treatment Outcome EDAT- 2002/09/27 06:00 MHDA- 2003/03/27 05:00 CRDT- 2002/09/27 06:00 PHST- 2002/09/27 06:00 [pubmed] PHST- 2003/03/27 05:00 [medline] PHST- 2002/09/27 06:00 [entrez] AID - 10.2169/internalmedicine.41.734 [doi] PST - ppublish SO - Intern Med. 2002 Sep;41(9):734-7. doi: 10.2169/internalmedicine.41.734.