PMID- 12358853
OWN - NLM
STAT- MEDLINE
DCOM- 20030321
LR  - 20191106
IS  - 0960-7420 (Print)
IS  - 0960-7420 (Linking)
VI  - 29
IP  - 5
DP  - 2002 Oct
TI  - Characterization of the NRAMP1 (SLC11A1) gene in the horse (Equus caballus L.).
PG  - 423-9
AB  - The complete coding cDNA sequence of the horse NRAMP1 (SLC11A1) gene was 
      determined (GenBank accession number AF354445). The nucleotide sequence of the 
      horse NRAMP1 gene is similar to sequences of this gene in other species. The gene 
      contains 15 exons whose total length of 1,635 bp corresponds to 544 amino acids 
      constituting the resulting putative protein. Hydrophobicity profile analysis of 
      the deduced horse NRAMP1 gene product showed a nearly identical structure with 
      the mouse NRAMP1 protein. The gene was found to be located on the short arm of 
      ECA 6p12-13 by fluorescence in situ hybridization (FISH) analysis. Five allelic 
      variants of the 5' untranslated region (UTR) were identified at the nucleotide 
      sequence level. PCR-RFLP polymorphisms for NlaIII, TaqI, MspI and AciI were 
      detected. Four out of five alleles could be detected using TaqI and MspI 
      restriction enzymes. Their haplotype frequencies were different in four 
      genetically distinct horse breeds.
FAU - Matiasovic, J
AU  - Matiasovic J
AD  - Faculty of Veterinary Medicine, Institute of Genetics, Brno 612 42, Czech 
      Republic.
FAU - Kubickova, S
AU  - Kubickova S
FAU - Musilova, P
AU  - Musilova P
FAU - Rubes, J
AU  - Rubes J
FAU - Horin, P
AU  - Horin P
LA  - eng
SI  - GENBANK/AG354445
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Eur J Immunogenet
JT  - European journal of immunogenetics : official journal of the British Society for 
      Histocompatibility and Immunogenetics
JID - 9106962
RN  - 0 (5' Untranslated Regions)
RN  - 0 (Cation Transport Proteins)
RN  - 0 (natural resistance-associated macrophage protein 1)
SB  - IM
MH  - 5' Untranslated Regions/genetics
MH  - Amino Acid Sequence
MH  - Animals
MH  - Base Sequence
MH  - Cation Transport Proteins/*genetics
MH  - Horses
MH  - Hydrophobic and Hydrophilic Interactions
MH  - Molecular Sequence Data
MH  - Physical Chromosome Mapping
MH  - Polymerase Chain Reaction
MH  - Polymorphism, Restriction Fragment Length
MH  - Sequence Analysis, DNA
EDAT- 2002/10/03 04:00
MHDA- 2003/03/22 04:00
CRDT- 2002/10/03 04:00
PHST- 2002/10/03 04:00 [pubmed]
PHST- 2003/03/22 04:00 [medline]
PHST- 2002/10/03 04:00 [entrez]
AID - 348 [pii]
AID - 10.1046/j.1365-2370.2002.00348.x [doi]
PST - ppublish
SO  - Eur J Immunogenet. 2002 Oct;29(5):423-9. doi: 10.1046/j.1365-2370.2002.00348.x.