PMID- 12373247 OWN - NLM STAT- MEDLINE DCOM- 20030204 LR - 20190916 IS - 0894-7317 (Print) IS - 0894-7317 (Linking) VI - 15 IP - 10 Pt 1 DP - 2002 Oct TI - Left atrial inflow propagation rate: a new transesophageal echocardiographic index of preload. PG - 1057-64 AB - We postulated that the rate of blood propagating into the left atrium from the left upper pulmonic vein would be a useful measure of pulmonary capillary wedge pressure (PCWP). In 23 adult patients who were critically ill (ie, study group) and receiving mechanical ventilation, color M-mode multiplane transesophageal echocardiography was used to measure left atrial inflow propagation rate (LAIF-PR) as a potential index of PCWP measured by right heart catheterization. LAIF-PR was measured in systole and diastole as the slope of the color M-mode signal entering the left atrium from the left upper pulmonic vein. Correlation with PCWP was good for systolic (r = -0.847, P < .0001) and diastolic (r = -0.78, P < .0001) LAIF-PR. The reliability of univariate linear regression equations derived from the study group was tested in 29 subsequent patients (ie, testing group). Measured PCWP was accurately estimated within 5 mm Hg in 85% (22 of 26 patients) and 68% (17 of 25 patients) of the testing group by systolic and diastolic LAIF-PR, respectively. Color M-mode transesophageal echocardiography-derived LAIF-PR, particularly in systole, is a promising new index to estimate PCWP in patients who are critically ill. FAU - Stoddard, Marcus F AU - Stoddard MF AD - Department of Medicine, Division of Cardiology, University of Louisville, KY 40202, USA. mfstod01@gwise.louisville.edu FAU - Longaker, Rita A AU - Longaker RA FAU - Calzada, Norberto AU - Calzada N LA - eng PT - Comparative Study PT - Journal Article PL - United States TA - J Am Soc Echocardiogr JT - Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography JID - 8801388 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Atrial Function, Left/*physiology MH - Chi-Square Distribution MH - *Echocardiography, Transesophageal MH - Female MH - Heart Atria/diagnostic imaging MH - Hemodynamics/physiology MH - Humans MH - Male MH - Middle Aged MH - Observer Variation MH - Pulmonary Wedge Pressure/*physiology MH - Reproducibility of Results EDAT- 2002/10/10 04:00 MHDA- 2003/02/05 04:00 CRDT- 2002/10/10 04:00 PHST- 2002/10/10 04:00 [pubmed] PHST- 2003/02/05 04:00 [medline] PHST- 2002/10/10 04:00 [entrez] AID - S0894731702001001 [pii] AID - 10.1067/mje.2002.121667 [doi] PST - ppublish SO - J Am Soc Echocardiogr. 2002 Oct;15(10 Pt 1):1057-64. doi: 10.1067/mje.2002.121667.