PMID- 12373473
OWN - NLM
STAT- MEDLINE
DCOM- 20030306
LR  - 20191210
IS  - 0342-4642 (Print)
IS  - 0342-4642 (Linking)
VI  - 28
IP  - 10
DP  - 2002 Oct
TI  - Evaluation of a noninvasive method for cardiac output measurement in critical 
      care patients.
PG  - 1470-4
AB  - OBJECTIVE: Thermodilution (TD) is the gold standard to monitor cardiac output 
      (CO) in critical care. However, there is concern about the safety of 
      right-ventricular catheterization. The CO(2) rebreathing technique allows 
      noninvasive CO determination by means of the indirect Fick principle. Our 
      objectives were: (a) to assess the accuracy of a new system of CO measurement 
      using the CO(2) partial rebreathing method (PRCO); (b) to evaluate whether the 
      PRCO itself may induce changes in CO. DESIGN AND SETTING: Prospective study in 
      the intensive care department in a university-affiliated hospital. PATIENTS: 
      Twenty-two mechanically ventilated critically ill patients. INTERVENTIONS: CO 
      measured simultaneously by PRCO and TDCO. MEASUREMENTS AND RESULTS: PRCO and TDCO 
      values were compared by concordance analysis. Stability of cardiac output during 
      PRCO was evaluated by comparing the TDCO measurements before, during, and after 
      the partial rebreathing period using analysis of variance. From a total of 79 
      valid sets of measurements, bias and precision was calculated at -0.18+/-1.39 
      l/min. The concordance analysis of lower and intermediate CO values (<7 l/min) 
      yielded a bias and precision calculation of -0.07+/-0.91 l/min. No changes in 
      hemodynamics were observed during the partial rebreathing period. CONCLUSIONS: 
      The noninvasive partial CO(2) rebreathing technique may be an alternative method 
      for CO determination in mechanically ventilated critically ill patients. The 
      rebreathing maneuver alone does not induce changes in CO.
FAU - Murias, Gaston E
AU  - Murias GE
AD  - Critical Care Center, Hospital San Martin, La Plata, Argentina.
FAU - Villagra, Ana
AU  - Villagra A
FAU - Vatua, Sara
AU  - Vatua S
FAU - del Mar Fernandez, Maria
AU  - del Mar Fernandez M
FAU - Solar, Hector
AU  - Solar H
FAU - Ochagavia, Ana
AU  - Ochagavia A
FAU - Fernandez, Rafael
AU  - Fernandez R
FAU - Lopez Aguilar, Josefina
AU  - Lopez Aguilar J
FAU - Romero, Pablo V
AU  - Romero PV
FAU - Blanch, Lluis
AU  - Blanch L
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20020904
PL  - United States
TA  - Intensive Care Med
JT  - Intensive care medicine
JID - 7704851
RN  - 142M471B3J (Carbon Dioxide)
SB  - IM
MH  - Breath Tests
MH  - Carbon Dioxide/analysis
MH  - *Cardiac Output
MH  - Critical Care/*methods
MH  - Hospitals, University
MH  - Humans
MH  - Intensive Care Units
MH  - Monitoring, Physiologic/*methods
MH  - Prospective Studies
MH  - *Respiration, Artificial
MH  - Spain
EDAT- 2002/10/10 04:00
MHDA- 2003/03/07 04:00
CRDT- 2002/10/10 04:00
PHST- 2002/02/11 00:00 [received]
PHST- 2002/07/26 00:00 [accepted]
PHST- 2002/10/10 04:00 [pubmed]
PHST- 2003/03/07 04:00 [medline]
PHST- 2002/10/10 04:00 [entrez]
AID - 10.1007/s00134-002-1477-1 [doi]
PST - ppublish
SO  - Intensive Care Med. 2002 Oct;28(10):1470-4. doi: 10.1007/s00134-002-1477-1. Epub 
      2002 Sep 4.