PMID- 12374589
OWN - NLM
STAT- MEDLINE
DCOM- 20021126
LR  - 20191106
IS  - 1090-3798 (Print)
IS  - 1090-3798 (Linking)
VI  - 6
IP  - 4
DP  - 2002
TI  - Frequent seizures with elevated interleukin-6 at the eruptive stage of exanthema 
      subitum.
PG  - 221-3
AB  - A 15-month-old girl developed frequent seizures at the eruptive stage of 
      exanthema subitum. The eruption persisted for 2 weeks. Serum immunoglobulin G 
      antibody to human herpes virus type 6 (HHV-6) increased markedly. Interleukin-6 
      was elevated whereas HHV-6 deoxyribonucleic acid was not detected in 
      cerebrospinal fluid. These findings suggest that immune-mediated reactions after 
      HHV-6 infection rather than direct action of active HHV-6 are responsible for 
      frequent seizures in this case.
FAU - Go, Tohshin
AU  - Go T
AD  - Department of Paediatrics, Otsu Red Cross Hospital, Otsu, Japan. 
      masumigo@mbox.kyoto-inet.or.jp
FAU - Nakamura, Kenji
AU  - Nakamura K
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - England
TA  - Eur J Paediatr Neurol
JT  - European journal of paediatric neurology : EJPN : official journal of the 
      European Paediatric Neurology Society
JID - 9715169
RN  - 0 (Antibodies, Viral)
RN  - 0 (Immunoglobulin M)
RN  - 0 (Interleukin-6)
SB  - IM
CIN - Eur J Paediatr Neurol. 2003;7(1):47; author reply 48. PMID: 12615174
MH  - Acute Disease
MH  - Antibodies, Viral/blood/immunology
MH  - Electroencephalography
MH  - Exanthema Subitum/blood/*complications/*immunology
MH  - Female
MH  - Herpesvirus 6, Human/immunology/metabolism
MH  - Humans
MH  - Immunoglobulin M/blood/immunology
MH  - Infant, Newborn
MH  - Interleukin-6/*immunology
MH  - *Periodicity
MH  - Seizures/*complications/diagnosis
MH  - Severity of Illness Index
EDAT- 2002/10/11 04:00
MHDA- 2002/11/28 04:00
CRDT- 2002/10/11 04:00
PHST- 2002/10/11 04:00 [pubmed]
PHST- 2002/11/28 04:00 [medline]
PHST- 2002/10/11 04:00 [entrez]
AID - S1090379802905970 [pii]
AID - 10.1053/ejpn.2002.0597 [doi]
PST - ppublish
SO  - Eur J Paediatr Neurol. 2002;6(4):221-3. doi: 10.1053/ejpn.2002.0597.