PMID- 12408260
OWN - NLM
STAT- MEDLINE
DCOM- 20030211
LR  - 20190513
IS  - 1099-5129 (Print)
IS  - 1099-5129 (Linking)
VI  - 4
IP  - 4
DP  - 2002 Oct
TI  - Ventricular activation and recovery measured in electrocardiographic limb leads 
      correlate with measurements from specific areas in body surface mapping.
PG  - 401-10
AB  - AIMS: Dispersion of ventricular depolarization-repolarization in 12-lead 
      electrocardiograms (ECGs) has been reported to provide noninvasive information on 
      arrhythmogenicity. However, there are two methods to calculate the dispersion 
      from ECGs including and excluding limb leads. The aim of this study was to 
      examine whether temporal parameters from limb leads represent activation and 
      repolarization of a particular part of the body surface. METHODS AND RESULTS: We 
      compared the temporal parameters of activation time (AT), activation-recovery 
      interval (ARI), and recovery time (RT) from limb leads of ECGs with those from an 
      87-lead body surface maps. The study population consisted of 50 normal subjects 
      (25 men and 25 women, 19.4 +/- 1.6 years). The temporal parameters in leads I, 
      II, and III were highly (r > 0.9) correlated with those in unipolar leads over 
      the left lateral, left lower, and right lower chest, respectively. The temporal 
      parameters in leads aVR, aVL, and aVF showed a significant correlation (r > 0.8) 
      with those in unipolar leads over the right upper, left upper, and lower anterior 
      chest, respectively. The mean AT, ARI, and RT from each limb lead of ECG were 
      almost the same as those of unipolar leads over the corresponding areas of the 
      body surface. CONCLUSIONS: These findings suggest that ATs, ARIs, and RTs from 
      limb leads may represent those from unipolar leads of particular areas over the 
      body surface in normal subjects. The temporal parameters from limb leads of ECGs 
      may provide information on activation and repolarization as well as the 
      precordial leads of ECGs.
FAU - Sawada, T
AU  - Sawada T
AD  - First Department of Internal Medicine, Nagoya University, School of Medicine, 
      Japan.
FAU - Hirai, M
AU  - Hirai M
FAU - Akahoshi, M
AU  - Akahoshi M
FAU - Inden, Y
AU  - Inden Y
FAU - Yoshida, Y
AU  - Yoshida Y
FAU - Ishihara, D
AU  - Ishihara D
FAU - Yamada, K
AU  - Yamada K
FAU - Takada, Y
AU  - Takada Y
FAU - Tanaka, T
AU  - Tanaka T
FAU - Takada, Y
AU  - Takada Y
FAU - Kondo, T
AU  - Kondo T
FAU - Murohara, T
AU  - Murohara T
LA  - eng
PT  - Journal Article
PL  - England
TA  - Europace
JT  - Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal 
      of the working groups on cardiac pacing, arrhythmias, and cardiac cellular 
      electrophysiology of the European Society of Cardiology
JID - 100883649
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - *Body Surface Potential Mapping
MH  - Female
MH  - Heart Conduction System/*physiology
MH  - Humans
MH  - Male
EDAT- 2002/11/01 04:00
MHDA- 2003/02/13 04:00
CRDT- 2002/11/01 04:00
PHST- 2002/11/01 04:00 [pubmed]
PHST- 2003/02/13 04:00 [medline]
PHST- 2002/11/01 04:00 [entrez]
AID - 10.1053/eupc.2002.0255 [doi]
PST - ppublish
SO  - Europace. 2002 Oct;4(4):401-10. doi: 10.1053/eupc.2002.0255.