PMID- 12408346 OWN - NLM STAT- MEDLINE DCOM- 20030325 LR - 20190906 IS - 0031-3025 (Print) IS - 0031-3025 (Linking) VI - 34 IP - 5 DP - 2002 Oct TI - Primitive neuroectodermal tumours of the uterus: a case report with cytological correlation and review of the literature. PG - 455-61 AB - A case of primitive neuroectodermal tumour (PNET) co-existing with endometrial adenocarcinoma of the uterus is reported in a 48-year-old female. Histologically, the neoplastic cells formed neuroectodermal rosettes and displayed ependymal differentiation. Focal positive immunohistochemical staining for synaptophysin, chromogranin A, CD57 and cytokeratins was noted. Merging imperceptibly with the neuroectodermal component were areas of endometrial adenocarcinoma and, to the best of our knowledge, this report represents the second case of a uterine PNET with an admixed mullerian component. The patient was disease-free 6 months following surgical resection of the tumour. The literature on this uncommon entity is critically reviewed and the histogenesis, differential diagnoses and cytomorphological features of PNET are also discussed. FAU - Ng, Siok Bian AU - Ng SB AD - Department of Pathology, Singapore General Hospital, Singapore. siokbian@hotmail.com FAU - Sirrampalam, Kesavan AU - Sirrampalam K FAU - Chuah, Khoon Leong AU - Chuah KL LA - eng PT - Case Reports PT - Journal Article PT - Review PL - England TA - Pathology JT - Pathology JID - 0175411 RN - 0 (Biomarkers, Tumor) RN - 0 (Neoplasm Proteins) SB - IM MH - Adenocarcinoma/chemistry/*pathology/surgery MH - Ascitic Fluid/pathology MH - Biomarkers, Tumor/analysis MH - Endometrial Neoplasms/chemistry/*pathology/surgery MH - Female MH - Humans MH - Immunohistochemistry MH - Middle Aged MH - Neoplasm Proteins/analysis MH - Neoplasms, Multiple Primary/chemistry/*pathology MH - Neuroectodermal Tumors, Primitive, Peripheral/chemistry/*pathology/surgery MH - Peritoneal Lavage MH - Treatment Outcome RF - 21 EDAT- 2002/11/01 04:00 MHDA- 2003/03/26 05:00 CRDT- 2002/11/01 04:00 PHST- 2002/11/01 04:00 [pubmed] PHST- 2003/03/26 05:00 [medline] PHST- 2002/11/01 04:00 [entrez] AID - 10.1080/0031302021000009397 [doi] PST - ppublish SO - Pathology. 2002 Oct;34(5):455-61. doi: 10.1080/0031302021000009397.