PMID- 12428815
OWN - NLM
STAT- MEDLINE
DCOM- 20030213
LR  - 20231114
IS  - 0160-9289 (Print)
IS  - 1932-8737 (Electronic)
IS  - 0160-9289 (Linking)
VI  - 25
IP  - 11 Suppl 1
DP  - 2002 Nov
TI  - Defining the scope of evidence-based practice for low-molecular-weight heparin 
      therapy in high-risk patients with unstable angina and non-ST-elevation 
      myocardial infarction.
PG  - I16-22
AB  - Various therapies have been utilized for the treatment of unstable angina and 
      non-ST-elevation myocardial infarction (NSTEMI). Each therapy has both advantages 
      and disadvantages with regard to clinical outcomes and an increased risk of 
      bleeding. One emerging primary therapy is low-molecular-weight heparin (LMWH). 
      Concerns have emerged, however, over the use of LMWH in patients going to the 
      catheterization laboratory or who receive platelet glycoprotein IIb/IIIa 
      inhibitors. Available trial data point to the safety and efficacy of LMWH in 
      these patients. Eventually, LMWH will probably replace unfractionated heparin 
      (UFH) for the majority of patients with acute coronary syndromes (ACS). At 
      present, however, practitioners need to consider individually how comfortable 
      they are with the available data.
FAU - Ferguson, James J
AU  - Ferguson JJ
AD  - Cardiology Research, St Luke's Episcopal Hospital, Texas Heart Institute, Houston 
      77030, USA. jferguson100@hotmail.com
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Clin Cardiol
JT  - Clinical cardiology
JID - 7903272
RN  - 0 (Anticoagulants)
RN  - 0 (Heparin, Low-Molecular-Weight)
SB  - IM
MH  - Acute Disease
MH  - Angina, Unstable/*drug therapy
MH  - Anticoagulants/therapeutic use
MH  - Cardiac Catheterization
MH  - *Evidence-Based Medicine
MH  - Heparin, Low-Molecular-Weight/*therapeutic use
MH  - Humans
MH  - Myocardial Infarction/*drug therapy
MH  - Risk
PMC - PMC6654075
EDAT- 2002/11/14 04:00
MHDA- 2003/02/14 04:00
PMCR- 2007/07/05
CRDT- 2002/11/14 04:00
PHST- 2002/11/14 04:00 [pubmed]
PHST- 2003/02/14 04:00 [medline]
PHST- 2002/11/14 04:00 [entrez]
PHST- 2007/07/05 00:00 [pmc-release]
AID - CLC4960251305 [pii]
AID - 10.1002/clc.4960251305 [doi]
PST - ppublish
SO  - Clin Cardiol. 2002 Nov;25(11 Suppl 1):I16-22. doi: 10.1002/clc.4960251305.