PMID- 12437547
OWN - NLM
STAT- MEDLINE
DCOM- 20030409
LR  - 20190910
IS  - 0736-8046 (Print)
IS  - 0736-8046 (Linking)
VI  - 19
IP  - 6
DP  - 2002 Nov-Dec
TI  - Thyroid function, autoantibodies, and HLA tissue typing in children with alopecia 
      areata.
PG  - 486-91
AB  - A total of 80 Kuwaiti children with alopecia areata (AA), without clinical 
      evidence of thyroid disease, were screened for the presence of thyroid 
      abnormalities, and 50 unrelated children with AA were tissue typed for human 
      leukocyte antigen (HLA) class I and class II antigens. Thyroid abnormalities were 
      detected in 14 children (17.5%). Among these, 11 children (14%) had thyroid 
      autoantibodies. These observations highlight the significance of screening for 
      thyroid abnormalities in children with chronic, recurrent, and/or extensive 
      disease. The Kuwaiti children with AA were observed to have a significant 
      association with HLA B21 (OR 18.850, 95% CI 4.404-80.677), B40 (OR 6.767, 95% CI 
      1.818-25.181), and HLA B12 (OR 4.833, 95% CI 1.198-19.505) antigens. These 
      findings differed from those reported elsewhere.
FAU - Nanda, Arti
AU  - Nanda A
AD  - Asad Al-Hamad Dermatology Center, Al-Sabah Hospital, Salmiya, Kuwait. 
      artinanda@hotmail.com
FAU - Alsaleh, Qasem A
AU  - Alsaleh QA
FAU - Al-Hasawi, Fowzia
AU  - Al-Hasawi F
FAU - Al-Muzairai, Ibrahim
AU  - Al-Muzairai I
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Pediatr Dermatol
JT  - Pediatric dermatology
JID - 8406799
RN  - 0 (Autoantibodies)
RN  - 0 (Histocompatibility Antigens Class I)
RN  - 0 (Histocompatibility Antigens Class II)
SB  - IM
MH  - Alopecia Areata/complications/*genetics/*immunology
MH  - Autoantibodies/*analysis
MH  - Case-Control Studies
MH  - Chi-Square Distribution
MH  - Child
MH  - Child, Preschool
MH  - Enzyme-Linked Immunosorbent Assay
MH  - Histocompatibility Antigens Class I/*genetics
MH  - Histocompatibility Antigens Class II/*genetics
MH  - Histocompatibility Testing
MH  - Humans
MH  - Infant
MH  - Kuwait
MH  - Thyroid Diseases/complications/*immunology
MH  - Thyroid Function Tests
EDAT- 2002/11/20 04:00
MHDA- 2003/04/10 05:00
CRDT- 2002/11/20 04:00
PHST- 2002/11/20 04:00 [pubmed]
PHST- 2003/04/10 05:00 [medline]
PHST- 2002/11/20 04:00 [entrez]
AID - 0216 [pii]
AID - 10.1046/j.1525-1470.2002.00216.x [doi]
PST - ppublish
SO  - Pediatr Dermatol. 2002 Nov-Dec;19(6):486-91. doi: 
      10.1046/j.1525-1470.2002.00216.x.