PMID- 12444377
OWN - NLM
STAT- MEDLINE
DCOM- 20030528
LR  - 20191210
IS  - 1234-1010 (Print)
IS  - 1234-1010 (Linking)
VI  - 8
IP  - 11
DP  - 2002 Nov
TI  - Predictors of change in exercise capacity after comprehensive COPD inpatient 
      rehabilitation.
PG  - CR740-5
AB  - BACKGROUND: In order to evaluate the factors associated with change in exercise 
      capacity after comprehensive inpatient Pulmonary Rehabilitation (IPR) we studied 
      132 consecutive adults with Chronic Obstructive Pulmonary Disease (COPD) 
      recovering from an acute exacerbation. MATERIAL/METHODS: Lung function, arterial 
      blood gases, and respiratory muscle strength were measured at baseline. Perceived 
      breathlessness (B), 6-minute walk distance (6MWD), dyspnea at rest and 
      post-exertion (D), hospital anxiety and depression (HAD), and health-related 
      quality of life were assessed before (T0) and after (T1) IPR. The patients were 
      divided into two groups depending on the change in 6MWD: Improvers (IM at least 
      +54 meters after IPR, n=81) or Non-Improvers (NIM, less than 54 meters or no 
      change, n=51). RESULTS: At T1 61% of the patients showed improvement as here 
      defined. The IM group showed lower 6MWD and higher B and resting-D at T0 than NIM 
      (p<0.05). A stepwise multiple regression analysis was performed using 6MWD change 
      as the dependent variable. and anthropometric and physiological measures at T0 as 
      the independent variables. This regression model explained 26% of the 
      6MWD-change; 6MWD and PaO2 significantly contributed to this model. CONCLUSIONS: 
      In COPD patients recovering from an acute exacerbation, the predicted change in 
      exercise capacity using anthropometric, demographic, clinical, and physiological 
      variables after 2 weeks of comprehensive IPR is likely to be low. The baseline 
      level of exercise performance and arterial oxygenation show the most consistent 
      correlation with change in walking ability in these patients.
FAU - Cilione, Carmela
AU  - Cilione C
AD  - Fondazione CdC Villa Pineta Division of Pneumology & Pulmonary Rehabilitation, 
      University of Modena-Reggio Emilia, Pavullo (MO), Italy.
FAU - Lorenzi, Cristina
AU  - Lorenzi C
FAU - Dell Orso, Daniela
AU  - Dell Orso D
FAU - Garuti, Giancarlo
AU  - Garuti G
FAU - Rossi, Giuseppina
AU  - Rossi G
FAU - Totaro, Lina
AU  - Totaro L
FAU - Clini, Enrico
AU  - Clini E
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Med Sci Monit
JT  - Medical science monitor : international medical journal of experimental and 
      clinical research
JID - 9609063
SB  - IM
MH  - Aged
MH  - *Exercise
MH  - Exercise Test/statistics & numerical data
MH  - Female
MH  - Forced Expiratory Volume
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Outcome Assessment, Health Care/*statistics & numerical data
MH  - Pulmonary Disease, Chronic Obstructive/*rehabilitation
MH  - Quality of Life
MH  - Regression Analysis
EDAT- 2002/11/22 04:00
MHDA- 2003/05/29 05:00
CRDT- 2002/11/22 04:00
PHST- 2002/11/22 04:00 [pubmed]
PHST- 2003/05/29 05:00 [medline]
PHST- 2002/11/22 04:00 [entrez]
AID - 2608 [pii]
PST - ppublish
SO  - Med Sci Monit. 2002 Nov;8(11):CR740-5.