PMID- 12449035 OWN - NLM STAT- MEDLINE DCOM- 20021209 LR - 20221207 IS - 0007-4551 (Print) IS - 0007-4551 (Linking) VI - 89 Spec No DP - 2002 Aug TI - [Combinations of platinum salts and gemcitabine in the treatment of non-small-cell lung cancer]. PG - S80-4 AB - Actually gemcitabine is a main drug in the treatment of non small cell lung cancer (NSCLC). The doublet gemcitabine and cisplatin is a standard treatment, widely used in the world. The review of the literature, and specially several recent randomised phase III trial in stage IV NSCLC demonstrates the reproducibility of the results, and a manageable toxicity which allows its use in preoperative setting in stages I, II and resectable III. The carboplatin-gemcitabine doublet is under investigation. FAU - Souquet, Pierre-Jean AU - Souquet PJ AD - Hospices civils de Lyon, Centre hospitalier Lyon-Sud, 69495 Pierre-Benite. pierre-jean.souquet@chu-lyon.fr FAU - Geriniere, Laurence AU - Geriniere L LA - fre PT - Comparative Study PT - Journal Article PT - Review TT - Les associations sels de platine-gemcitabine dans les traitements des cancers bronchiques non a petites cellules. PL - France TA - Bull Cancer JT - Bulletin du cancer JID - 0072416 RN - 0 (Taxoids) RN - 0W860991D6 (Deoxycytidine) RN - 15H5577CQD (Docetaxel) RN - 5V9KLZ54CY (Vinblastine) RN - 6PLQ3CP4P3 (Etoposide) RN - BG3F62OND5 (Carboplatin) RN - P88XT4IS4D (Paclitaxel) RN - Q20Q21Q62J (Cisplatin) RN - Q6C979R91Y (Vinorelbine) RN - 0 (Gemcitabine) SB - IM MH - Antineoplastic Combined Chemotherapy Protocols/adverse effects/*therapeutic use MH - Carboplatin/administration & dosage/adverse effects MH - Carcinoma, Non-Small-Cell Lung/*drug therapy/surgery MH - Cisplatin/administration & dosage/adverse effects MH - Clinical Trials, Phase III as Topic MH - Combined Modality Therapy MH - Deoxycytidine/administration & dosage/adverse effects/*analogs & derivatives MH - Docetaxel MH - Etoposide/administration & dosage/adverse effects MH - Gastrointestinal Diseases/chemically induced MH - Hematologic Diseases/chemically induced MH - Humans MH - Lung Neoplasms/drug therapy/*surgery MH - Neoadjuvant Therapy MH - Paclitaxel/administration & dosage/adverse effects/*analogs & derivatives MH - Pneumonectomy MH - Randomized Controlled Trials as Topic MH - Remission Induction MH - Reproducibility of Results MH - *Taxoids MH - Treatment Outcome MH - Vinblastine/administration & dosage/adverse effects/*analogs & derivatives MH - Vinorelbine MH - Gemcitabine RF - 20 EDAT- 2002/11/27 04:00 MHDA- 2002/12/10 04:00 CRDT- 2002/11/27 04:00 PHST- 2002/11/27 04:00 [pubmed] PHST- 2002/12/10 04:00 [medline] PHST- 2002/11/27 04:00 [entrez] PST - ppublish SO - Bull Cancer. 2002 Aug;89 Spec No:S80-4.