PMID- 12449249
OWN - NLM
STAT- MEDLINE
DCOM- 20021213
LR  - 20191106
IS  - 0931-1793 (Print)
IS  - 0931-1793 (Linking)
VI  - 49
IP  - 8
DP  - 2002 Oct
TI  - Detection and isolation of equine herpesviruses 1 and 4 from horses in Normandy: 
      an autopsy study of tissue distribution in relation to vaccination status.
PG  - 394-9
AB  - Equine herpesviruses type 1 and 4 (EHV-1 and EHV-4) are ubiquitous in the equine 
      population. One of their main properties is their ability to establish life-long 
      latent infections in their hosts even in those with natural or vaccine-induced 
      immunity. However, effect of vaccination status on prevalence and tissue tropism 
      was not established. In this study, EHV-1 and EHV-4 were detected by polymerase 
      chain reaction and by classical virus isolation from neural, epithelial and 
      lymphoid tissues collected from unvaccinated (33) or vaccinated (23) horses. The 
      percentage of EHV-1- and EHV-4-positive horses between vaccinates and 
      unvaccinates was similar. Both viruses were detected in all tissues of both 
      groups; in particular, lymph nodes draining the respiratory tract, nasal 
      epithelium and nervous ganglia [i.e. trigeminal ganglia (TG)], which represent 
      the main positive sites for EHV-1 and EHV-4. In vaccinated animals, the nervous 
      ganglia (i.e. TG) were less frequently positive than in unvaccinated animals. 
      Detection of positive TG was strongly correlated to the presence of EHV-1 in 
      nasal epithelium.
FAU - Taouji, S
AU  - Taouji S
AD  - AFSSA, Laboratoire d'etudes et de recherches en pathologie equine, Dozule, 
      France. s.taouji@dozule.afssa.fr
FAU - Collobert, C
AU  - Collobert C
FAU - Gicquel, B
AU  - Gicquel B
FAU - Sailleau, C
AU  - Sailleau C
FAU - Brisseau, N
AU  - Brisseau N
FAU - Moussu, C
AU  - Moussu C
FAU - Breuil, M F
AU  - Breuil MF
FAU - Pronost, S
AU  - Pronost S
FAU - Borchers, K
AU  - Borchers K
FAU - Zientara, S
AU  - Zientara S
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - J Vet Med B Infect Dis Vet Public Health
JT  - Journal of veterinary medicine. B, Infectious diseases and veterinary public 
      health
JID - 100955260
RN  - 0 (DNA Primers)
RN  - 0 (DNA, Viral)
RN  - 0 (Viral Vaccines)
SB  - IM
MH  - Animals
MH  - Autopsy
MH  - DNA Primers
MH  - DNA, Viral/genetics
MH  - France/epidemiology
MH  - Herpesviridae Infections/epidemiology/prevention & control/*veterinary
MH  - Herpesvirus 1, Equid/genetics/*immunology
MH  - Herpesvirus 4, Equid/genetics/*immunology
MH  - Horse Diseases/*epidemiology/*prevention & control/virology
MH  - Horses
MH  - Polymerase Chain Reaction/veterinary
MH  - *Viral Vaccines
EDAT- 2002/11/27 04:00
MHDA- 2002/12/17 04:00
CRDT- 2002/11/27 04:00
PHST- 2002/11/27 04:00 [pubmed]
PHST- 2002/12/17 04:00 [medline]
PHST- 2002/11/27 04:00 [entrez]
AID - 10.1046/j.1439-0450.2002.00590.x [doi]
PST - ppublish
SO  - J Vet Med B Infect Dis Vet Public Health. 2002 Oct;49(8):394-9. doi: 
      10.1046/j.1439-0450.2002.00590.x.