PMID- 12450051
OWN - NLM
STAT- MEDLINE
DCOM- 20021213
LR  - 20211203
IS  - 0022-3085 (Print)
IS  - 0022-3085 (Linking)
VI  - 97
IP  - 5
DP  - 2002 Nov
TI  - Wegener granulomatosis manifesting as meningitis. Case report.
PG  - 1229-32
AB  - The authors describe a unique presentation of Wegener granulomatosis (WG) 
      manifesting predominantly as meningitis. Magnetic resonance imaging demonstrated 
      diffuse meningeal enhancement, including the pia mater, in a 28-year-old man with 
      meningitis. A diagnosis of atypical WG was based on the findings of a dural 
      biopsy sample and an elevated cytoplasmic antineutrophil cytoplasmic antibody 
      (cANCA) titer, although the patient did not have any of the lesions common to WG. 
      Immunosuppressive therapy was quite effective. With treatment, the meningeal 
      enhancement resolved and the cANCA titer normalized. Meningeal granulomatosis as 
      the sole lesion in WG has never been reported in the literature. This atypical 
      course of WG should be noted.
FAU - Yasuhara, Takao
AU  - Yasuhara T
AD  - Department of Neurosurgery, Kagawa Rosai Hospital, Marugame City, Kagawa, Japan. 
      tyasu37@cc.okayama-u.ac.jp
FAU - Fukuhara, Toru
AU  - Fukuhara T
FAU - Nakagawa, Minoru
AU  - Nakagawa M
FAU - Terai, Yoshinori
AU  - Terai Y
FAU - Yoshino, Kimihiro
AU  - Yoshino K
FAU - Mizobuchi, Koichi
AU  - Mizobuchi K
FAU - Fujimoto, Shunichiro
AU  - Fujimoto S
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - J Neurosurg
JT  - Journal of neurosurgery
JID - 0253357
RN  - 0 (Antibodies, Antineutrophil Cytoplasmic)
SB  - IM
MH  - Adult
MH  - Antibodies, Antineutrophil Cytoplasmic/analysis
MH  - Granulomatosis with Polyangiitis/*complications/immunology/pathology/therapy
MH  - Humans
MH  - Immunosuppression Therapy
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Meningitis/diagnosis/*etiology
MH  - Tomography, X-Ray Computed
EDAT- 2002/11/27 04:00
MHDA- 2002/12/17 04:00
CRDT- 2002/11/27 04:00
PHST- 2002/11/27 04:00 [pubmed]
PHST- 2002/12/17 04:00 [medline]
PHST- 2002/11/27 04:00 [entrez]
AID - 10.3171/jns.2002.97.5.1229 [doi]
PST - ppublish
SO  - J Neurosurg. 2002 Nov;97(5):1229-32. doi: 10.3171/jns.2002.97.5.1229.