PMID- 12451730
OWN - NLM
STAT- MEDLINE
DCOM- 20021223
LR  - 20190916
IS  - 0042-8450 (Print)
IS  - 0042-8450 (Linking)
VI  - 59
IP  - 5
DP  - 2002 Sep-Oct
TI  - [Antibiotic resistance in hospital strains of Enterococcus faecalis and 
      Enterococcus faecium].
PG  - 499-506
AB  - The aim of this study was to determine the resistance of Enterococcus faecalis 
      (E. faecalis) and Enterococcus faecium (E. faecium) to penicillin, ampicillin, 
      vancomycin, teicoplanin, gentamicin (high level), streptomycin (high level), 
      oxytetracycline, chloramphenicol, rifampin, erythromycin, ciprofloxacin, 
      norfloxacin, and nitrofurantoin from clinical specimens during 1999. The 
      resistance of enterococci to antibiotics was determined by disk diffusion and 
      dilution methods according to the American National Committee for Clinical 
      Laboratory Standards guidelines. The production of beta-lactamase was determined 
      by nitrocefin disks. In E. faecalis and E. faecium isolates (n = 111 and n = 48) 
      the frequency of the resistance to both penicillins was 0.9% and 89.6%, 
      respectively. All enterococci isolates were beta-lactamase negative. Only one 
      strain of E. faecium was vancomycin resistant (Van A fenotype). Among E. faecalis 
      isolates (n = 109) high level gentamicin resistance (HLGR), high level 
      streptomycin resistance (HLSR), and resistance to both agents was 52.3%, 50.4%, 
      and 43.7%, respectively. Among E. faecium isolates (n = 48) HLGR, HLSR, and to 
      both agents were 68.7%, 75%, and 62.5% respectively. The majority of E. faecium 
      isolates were resistant to both penicillin and ampicillin. E. faecalis remained 
      susceptible to penicillins. Moreover, there was a very high incidence of 
      enterococci resistant to high level aminoglycosides.
FAU - Mirovic, Veljko
AU  - Mirovic V
AD  - Vojnomedicinska akademija, ZPM-Institut za mikrobiologiju, Beograd.
LA  - srp
PT  - English Abstract
PT  - Journal Article
TT  - Rezistencija bolnickih sojeva Enterococcus faecalis i Enterococcus faecium na 
      antibiotike.
PL  - Serbia
TA  - Vojnosanit Pregl
JT  - Vojnosanitetski pregled
JID - 21530700R
SB  - IM
MH  - *Drug Resistance, Bacterial
MH  - Enterococcus faecalis/*drug effects/isolation & purification
MH  - Enterococcus faecium/*drug effects/isolation & purification
MH  - Humans
MH  - Inpatients
MH  - Microbial Sensitivity Tests
EDAT- 2002/11/28 04:00
MHDA- 2002/12/27 04:00
CRDT- 2002/11/28 04:00
PHST- 2002/11/28 04:00 [pubmed]
PHST- 2002/12/27 04:00 [medline]
PHST- 2002/11/28 04:00 [entrez]
AID - 10.2298/vsp0205499m [doi]
PST - ppublish
SO  - Vojnosanit Pregl. 2002 Sep-Oct;59(5):499-506. doi: 10.2298/vsp0205499m.