PMID- 12459511
OWN - NLM
STAT- MEDLINE
DCOM- 20030320
LR  - 20190701
IS  - 0304-3940 (Print)
IS  - 0304-3940 (Linking)
VI  - 335
IP  - 2
DP  - 2002 Dec 25
TI  - Mating behavior induces differential Arc expression in the main and accessory 
      olfactory bulbs of adult rats.
PG  - 111-4
AB  - The expression of activity-related cytoskeleton-associated protein, Arc, could be 
      useful as a marker for neuronal activity. We investigated Arc-immunoreactivity in 
      both the accessory olfactory bulb (AOB) and the main olfactory bulb (MOB) of 
      adult male rats in response to mating or exposure to female pheromones. Mating 
      behavior strongly enhanced the Arc-immunoreactivity in the granule cell layer of 
      the AOB. However, the enhancement of Arc-immunoreactivity by mating behavior was 
      not observed in the MOB. These results showed that Arc-immunoreactivity was 
      enhanced when the AOB received both afferent and efferent information during 
      mating behavior. Hence, the expression of Arc in the AOB directly associates the 
      pheromonal information with mating behavior. The AOB will provide a useful model 
      to investigate the function of Arc protein.
FAU - Matsuoka, Masato
AU  - Matsuoka M
AD  - Division of Neurobiology and Anatomy, Niigata University Graduate School of 
      Medical and Dental Sciences, Niigata, 951-8510, Niigata, Japan.
FAU - Yoshida-Matsuoka, Junko
AU  - Yoshida-Matsuoka J
FAU - Sugiura, Hiroko
AU  - Sugiura H
FAU - Yamagata, Kanato
AU  - Yamagata K
FAU - Ichikawa, Masumi
AU  - Ichikawa M
FAU - Norita, Masao
AU  - Norita M
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Ireland
TA  - Neurosci Lett
JT  - Neuroscience letters
JID - 7600130
RN  - 0 (Apoptosis Regulatory Proteins)
RN  - 0 (Immediate-Early Proteins)
RN  - 0 (Muscle Proteins)
RN  - 0 (Nol3 protein, rat)
RN  - 0 (Sex Attractants)
SB  - IM
MH  - Analysis of Variance
MH  - Animals
MH  - Apoptosis Regulatory Proteins
MH  - Female
MH  - Immediate-Early Proteins/biosynthesis
MH  - Immunoblotting
MH  - Immunohistochemistry
MH  - Male
MH  - Muscle Proteins/*biosynthesis/metabolism
MH  - Olfactory Bulb/cytology/*metabolism
MH  - Olfactory Pathways/cytology/metabolism
MH  - Random Allocation
MH  - Rats
MH  - Rats, Sprague-Dawley
MH  - Sex Attractants/pharmacology
MH  - Sexual Behavior, Animal/*physiology
EDAT- 2002/12/03 04:00
MHDA- 2003/03/21 04:00
CRDT- 2002/12/03 04:00
PHST- 2002/12/03 04:00 [pubmed]
PHST- 2003/03/21 04:00 [medline]
PHST- 2002/12/03 04:00 [entrez]
AID - S0304394002011874 [pii]
AID - 10.1016/s0304-3940(02)01187-4 [doi]
PST - ppublish
SO  - Neurosci Lett. 2002 Dec 25;335(2):111-4. doi: 10.1016/s0304-3940(02)01187-4.