PMID- 12467814
OWN - NLM
STAT- MEDLINE
DCOM- 20030313
LR  - 20190513
IS  - 1010-7940 (Print)
IS  - 1010-7940 (Linking)
VI  - 22
IP  - 6
DP  - 2002 Dec
TI  - Multivariate analysis of risk factors for hospital mortality in valvular 
      reoperations for prosthetic valve dysfunction.
PG  - 922-6
AB  - OBJECTIVES: The purpose of the study was to analyze risk factors for hospital 
      mortality in patients undergoing valvular reoperations for prosthetic valve 
      dysfunction. METHODS: We performed a prospective analysis of 146 patients who 
      underwent valvular reoperations for prosthetic valve dysfunction between July 
      1995 and June 1999 at the Heart Institute of the University of Sao Paulo Medical 
      School. Multivariate statistical analysis with logistic regression was used to 
      analyze preoperative and intraoperative variables to determine risk factors for 
      hospital mortality. RESULTS: The overall hospital mortality was 10.9% (16 
      patients). Univariate analysis showed that the following variables were 
      associated with higher mortality rates: advanced New York Heart Association 
      (NYHA) functional class, increased creatinine level, prolonged extracorporeal 
      circulation time and treatment of annular abscess. Logistic multivariate analysis 
      identified advanced NYHA functional class and a creatinine level higher than 1.5 
      mg/dl as independent predictors of hospital mortality. CONCLUSIONS: Advanced NYHA 
      functional class and higher creatinine levels were independent predictors of 
      hospital mortality in patients submitted for valvular reoperations for prosthetic 
      valve dysfunction.
FAU - de Almeida Brandao, Carlos Manuel
AU  - de Almeida Brandao CM
AD  - InCor-Heart Institute, University of Sao Paulo Medical School, Sao Paulo, Brazil. 
      carlos.brandao@incor.usp.br
FAU - Pomerantzeff, Pablo Maria Alberto
AU  - Pomerantzeff PM
FAU - Souza, Luciano Rapold
AU  - Souza LR
FAU - Tarasoutchi, Flavio
AU  - Tarasoutchi F
FAU - Grimberg, Max
AU  - Grimberg M
FAU - Ramires, Jose Antonio Franchini
AU  - Ramires JA
FAU - Almeida de Oliveira, Sergio
AU  - Almeida de Oliveira S
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Eur J Cardiothorac Surg
JT  - European journal of cardio-thoracic surgery : official journal of the European 
      Association for Cardio-thoracic Surgery
JID - 8804069
RN  - 0 (Biomarkers)
RN  - AYI8EX34EU (Creatinine)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Biomarkers/blood
MH  - Brazil/epidemiology
MH  - Child
MH  - Creatinine/blood
MH  - Female
MH  - Heart Valve Prosthesis
MH  - Heart Valve Prosthesis Implantation/*mortality
MH  - *Hospital Mortality
MH  - Humans
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Prognosis
MH  - Prospective Studies
MH  - Prosthesis Failure
MH  - Reoperation/mortality
MH  - Risk Factors
MH  - Severity of Illness Index
EDAT- 2002/12/07 04:00
MHDA- 2003/03/14 04:00
CRDT- 2002/12/07 04:00
PHST- 2002/12/07 04:00 [pubmed]
PHST- 2003/03/14 04:00 [medline]
PHST- 2002/12/07 04:00 [entrez]
AID - S1010794002005833 [pii]
AID - 10.1016/s1010-7940(02)00583-3 [doi]
PST - ppublish
SO  - Eur J Cardiothorac Surg. 2002 Dec;22(6):922-6. doi: 
      10.1016/s1010-7940(02)00583-3.