PMID- 1248100
OWN - NLM
STAT- MEDLINE
DCOM- 19760430
LR  - 20191021
IS  - 0009-9090 (Print)
IS  - 0009-9090 (Linking)
VI  - 6
IP  - 1
DP  - 1976 Jan
TI  - Measurement of specific IgE antibodies in nasal secretion--evidence for local 
      production.
PG  - 69-73
AB  - Serum levels of total and specific immunoglobulin E (IgE) have been determined by 
      radioimmunoassays in sixty-nine allergic subjects. The forty-one subjects with 
      mild symptoms were the most difficult to diagnose, since nine had IgE levels less 
      than 50 U/ml and nineteen had no detectable specific IgE antibodies. Samples of 
      nasal secretions were collected from these nineteen subjects and five were found 
      to have specific IgE antibodies, and in a further eight increased amounts of 
      total IgE. The possibility of locally produced IgE antibodies should therefore be 
      considered when using in vitro tests to diagnose mild or recently acquired 
      allergies, especially when serum IgE levels are less than 50 U/ml.
FAU - Merrett, T G
AU  - Merrett TG
FAU - Houri, M
AU  - Houri M
FAU - Mayer, A L
AU  - Mayer AL
FAU - Merrett, J
AU  - Merrett J
LA  - eng
PT  - Journal Article
PL  - England
TA  - Clin Allergy
JT  - Clinical allergy
JID - 0311172
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Humans
MH  - Immunoglobulin E/*analysis/biosynthesis
MH  - Nasal Mucosa/*immunology
MH  - Radioimmunoassay/methods
MH  - Respiratory Hypersensitivity/diagnosis/*immunology
EDAT- 1976/01/01 00:00
MHDA- 1976/01/01 00:01
CRDT- 1976/01/01 00:00
PHST- 1976/01/01 00:00 [pubmed]
PHST- 1976/01/01 00:01 [medline]
PHST- 1976/01/01 00:00 [entrez]
AID - 10.1111/j.1365-2222.1976.tb01413.x [doi]
PST - ppublish
SO  - Clin Allergy. 1976 Jan;6(1):69-73. doi: 10.1111/j.1365-2222.1976.tb01413.x.