PMID- 12491605 OWN - NLM STAT- MEDLINE DCOM- 20030304 LR - 20191210 IS - 0047-1860 (Print) IS - 0047-1860 (Linking) VI - 50 IP - 11 DP - 2002 Nov TI - [Revisited univariate delta check method for hematologic laboratories (I)--Usefulness for detection of specimen mix-up in patients with hematologic disorders]. PG - 1072-5 AB - We evaluated the delta check method for hematologic laboratories to detect specimen mix-up. We selected 271 patients with hematologic disorders and two types of investigation were conducted. The first investigation comprised statistical analysis, while the second involved evaluation of the procedure. From parameters of white blood cell, red blood cell, hemoglobin, hematocrit, mean corpuscular volume (MCV), mean corpuscular hemoglobin(MCH), mean corpuscular hemoglobin concentration (MCHC), and platelets, MCV was considered to represent the best single marker to detect artificial mix-up. About 98% of MCV delta values from one patient were within 3 fl. Conversely, 40% of MCV delta values in artificial mixups exceed 10 fl. No correlations between time interval and MCV delta values were detected. However, some cases were observed in which MCV delta values changed markedly over a short period of time even though the samples originated from one patient. In conclusion, we recommend investigation for specimen mix-up in cases where MCV delta values exceed 4 fl. FAU - Ohara, Tomoko AU - Ohara T AD - Department of Clinical Laboratory Medicine, Jichi Medical School, Kawachi-gun, Tochigi-pref. 329-0498. FAU - Itoh, Kouichi AU - Itoh K LA - jpn PT - Evaluation Study PT - Journal Article PL - Japan TA - Rinsho Byori JT - Rinsho byori. The Japanese journal of clinical pathology JID - 2984781R SB - IM MH - *Clinical Laboratory Techniques MH - Diagnostic Errors/*prevention & control MH - Erythrocyte Indices MH - Hematologic Diseases/blood/*diagnosis MH - Hematologic Tests/*methods MH - Humans MH - *Quality Control MH - ROC Curve MH - *Specimen Handling MH - Time Factors EDAT- 2002/12/21 04:00 MHDA- 2003/03/05 04:00 CRDT- 2002/12/21 04:00 PHST- 2002/12/21 04:00 [pubmed] PHST- 2003/03/05 04:00 [medline] PHST- 2002/12/21 04:00 [entrez] PST - ppublish SO - Rinsho Byori. 2002 Nov;50(11):1072-5.