PMID- 12498266
OWN - NLM
STAT- MEDLINE
DCOM- 20030514
LR  - 20191210
IS  - 0021-9673 (Print)
IS  - 0021-9673 (Linking)
VI  - 979
IP  - 1-2
DP  - 2002 Dec 6
TI  - Analysis of illicit amphetamine seizures by capillary zone electrophoresis.
PG  - 345-52
AB  - Capillary zone electrophoresis was applied for the determination of amphetamine 
      and related substances in seized drugs. A buffer made of 0.1 M phosphoric acid 
      adjusted to pH 3.0 with triethanolamine was selected. With this background 
      electrolyte, triethanolamine is adsorbed to the capillary wall and the 
      electroosmotic flow is reversed. This gives rise to peaks with good symmetry, 
      high efficiency and reproducible migration times. The separation of the different 
      analytes was performed in a fused-silica capillary thermostatted at 25 degrees C 
      and the applied voltage was 25 kV. Under these experimental conditions, 
      amphetamine, methamphetamine, 3,4-methylenedioxyamphetamine, 
      3,4-methylenedioxymethamphetamine (MDMA), 3,4-methylenedioxyethamphetamine, 
      N-methyl-1-(1,3-benzodioxol-5-yl)-2-butamine and ephedrine were resolved within 8 
      min and without interference from adulterants usually found in illicit powders. 
      Their identification by the migration time was confirmed by their UV spectra 
      recorded with a diode array UV detector (190-350 nm). The selected method was 
      then applied to identify these substances in illicit tablets known as "Ecstasy" 
      and the MDMA determined in these samples according to a laboratory validation 
      procedure.
FAU - Piette, Veronique
AU  - Piette V
AD  - Laboratory of Drug Analysis, Scientific Institute of Public Health-Louis Pasteur, 
      Rue Juliette Wytsman 14, B-1050 Brussels, Belgium. veronique.piette@iph.fgov.be
FAU - Parmentier, Frans
AU  - Parmentier F
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Amphetamines)
RN  - 0 (Buffers)
RN  - 0 (Illicit Drugs)
SB  - IM
MH  - Amphetamines/*analysis
MH  - Buffers
MH  - Electrophoresis, Capillary/*methods
MH  - Hydrogen-Ion Concentration
MH  - Illicit Drugs/*analysis
MH  - Reproducibility of Results
MH  - Spectrophotometry, Ultraviolet
EDAT- 2002/12/25 04:00
MHDA- 2003/05/15 05:00
CRDT- 2002/12/25 04:00
PHST- 2002/12/25 04:00 [pubmed]
PHST- 2003/05/15 05:00 [medline]
PHST- 2002/12/25 04:00 [entrez]
AID - S0021-9673(02)01405-X [pii]
AID - 10.1016/s0021-9673(02)01405-x [doi]
PST - ppublish
SO  - J Chromatogr A. 2002 Dec 6;979(1-2):345-52. doi: 10.1016/s0021-9673(02)01405-x.