PMID- 12504712 OWN - NLM STAT- MEDLINE DCOM- 20030127 LR - 20190627 IS - 0002-9394 (Print) IS - 0002-9394 (Linking) VI - 135 IP - 1 DP - 2003 Jan TI - Acute multifocal placoid pigment epitheliopathy-like lesion as an early presentation of subacute sclerosing panencephalitis. PG - 103-5 AB - PURPOSE: To report a case of acute multifocal placoid pigment epitheliopathy (AMPPE)-like lesion as an early presentation of subacute sclerosing panencephalitis (SSPE). DESIGN: Observational case report. METHODS: A 21-year-old woman presented with a profound loss of vision in the left eye. The initial clinical picture was characterized by a whitish infiltration of the macular area and papillary edema in the left eye. Six days later multiple chorioretinal infiltrations were present in the peripheral fundus of the left eye, which led to the diagnosis of AMPPE. RESULTS: During the following year, a gradual change in her personality developed. The diagnosis of SSPE was made by cerebrospinal fluid examination. Her clinical condition deteriorated rapidly, and she died. CONCLUSIONS: AMPPE can be accompanied by central nervous system involvement. We wish to emphasize the importance of considering the diagnosis of SSPE in cases of AMPPE. FAU - Floegel, Ingrid AU - Floegel I AD - Department of Ophthalmology, Karl Franzens University Graz, Graz, Austria. ingrid.floegel@kfunigraz.ac.at FAU - Haas, Anton AU - Haas A FAU - El-Shabrawi, Yosuf AU - El-Shabrawi Y LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Am J Ophthalmol JT - American journal of ophthalmology JID - 0370500 SB - IM MH - Adult MH - Fatal Outcome MH - Female MH - Fluorescein Angiography MH - Humans MH - Pigment Epithelium of Eye/*pathology MH - Retinal Diseases/*diagnosis MH - Subacute Sclerosing Panencephalitis/*diagnosis EDAT- 2002/12/31 04:00 MHDA- 2003/01/28 04:00 CRDT- 2002/12/31 04:00 PHST- 2002/12/31 04:00 [pubmed] PHST- 2003/01/28 04:00 [medline] PHST- 2002/12/31 04:00 [entrez] AID - S0002939402018494 [pii] AID - 10.1016/s0002-9394(02)01849-4 [doi] PST - ppublish SO - Am J Ophthalmol. 2003 Jan;135(1):103-5. doi: 10.1016/s0002-9394(02)01849-4.