PMID- 12505267
OWN - NLM
STAT- MEDLINE
DCOM- 20030115
LR  - 20190816
IS  - 0165-4608 (Print)
IS  - 0165-4608 (Linking)
VI  - 138
IP  - 2
DP  - 2002 Oct 15
TI  - Sensitivity of detection of B-cell lymphoma in bone marrow by fluorescence in 
      situ hybridization.
PG  - 174-6
AB  - Fluorescence in situ hybridization (FISH) was used in a retrospective study of 
      bone marrow aspirate specimens submitted for conventional cytogenetic analysis 
      with an indication of B-cell lymphoma. About 50% of cytogenetically normal 
      samples, which had been identified as containing lymphoma by pathology, showed 
      small cell populations with an IGH gene rearrangement by FISH. This study 
      demonstrates that FISH scoring of 750 nuclei provides a 99% chance of identifying 
      the presence of lymphoma with a 14q32 aberration when this population constitutes 
      approximately 8% of the bone marrow.
FAU - Juenger, Christopher
AU  - Juenger C
AD  - Genetics and IVF Institute, Fairfax, VA 22031, USA.
FAU - Stanley, Wayne S
AU  - Stanley WS
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Cancer Genet Cytogenet
JT  - Cancer genetics and cytogenetics
JID - 7909240
RN  - 0 (Immunoglobulin Heavy Chains)
SB  - IM
MH  - Bone Marrow/*pathology
MH  - Chromosome Aberrations
MH  - Chromosomes, Human, Pair 14/genetics
MH  - Humans
MH  - Immunoglobulin Heavy Chains/genetics
MH  - In Situ Hybridization, Fluorescence/*methods
MH  - Lymphoma, B-Cell/*diagnosis/*genetics
MH  - Sensitivity and Specificity
EDAT- 2002/12/31 04:00
MHDA- 2003/01/16 04:00
CRDT- 2002/12/31 04:00
PHST- 2002/12/31 04:00 [pubmed]
PHST- 2003/01/16 04:00 [medline]
PHST- 2002/12/31 04:00 [entrez]
AID - S0165460802005691 [pii]
AID - 10.1016/s0165-4608(02)00569-1 [doi]
PST - ppublish
SO  - Cancer Genet Cytogenet. 2002 Oct 15;138(2):174-6. doi: 
      10.1016/s0165-4608(02)00569-1.