PMID- 1250700
OWN - NLM
STAT- MEDLINE
DCOM- 19760430
LR  - 20190501
IS  - 0305-1048 (Print)
IS  - 1362-4962 (Electronic)
IS  - 0305-1048 (Linking)
VI  - 3
IP  - 1
DP  - 1976 Jan
TI  - A new synthesis of inosine from 
      5-amino-1-beta-D-ribofuranosyl-4-imidazole-carboxamide.
PG  - 231-5
AB  - Inosine was prepared (15% yield) by treatment of 
      5-amino-1-beta-D-ribofuranosyl-4-imidazolecarboxamide (AICA-riboside) with 
      chloroform in the presence of sodium methoxide. This ring closure can be 
      reasonably explained by assuming the formation of dichlorocarbene from chloroform 
      and alkali. Carbon tetrachloride or hexachloroethane as a carbene source was more 
      effective for the ring closure of AICA-riboside, giving inosine in 48% and 51% 
      yields respectively.
FAU - Okutsu, M
AU  - Okutsu M
FAU - Yamazaki, A
AU  - Yamazaki A
LA  - eng
PT  - Journal Article
PL  - England
TA  - Nucleic Acids Res
JT  - Nucleic acids research
JID - 0411011
RN  - 0 (Imidazoles)
RN  - 0 (Ribonucleosides)
RN  - 5A614L51CT (Inosine)
SB  - IM
MH  - Cyclization
MH  - Imidazoles
MH  - Inosine/*chemical synthesis
MH  - Methods
MH  - Ribonucleosides
PMC - PMC342890
EDAT- 1976/01/01 00:00
MHDA- 1976/01/01 00:01
CRDT- 1976/01/01 00:00
PHST- 1976/01/01 00:00 [pubmed]
PHST- 1976/01/01 00:01 [medline]
PHST- 1976/01/01 00:00 [entrez]
AID - 10.1093/nar/3.1.231 [doi]
PST - ppublish
SO  - Nucleic Acids Res. 1976 Jan;3(1):231-5. doi: 10.1093/nar/3.1.231.