PMID- 12507819
OWN - NLM
STAT- MEDLINE
DCOM- 20040106
LR  - 20211203
IS  - 0198-8859 (Print)
IS  - 0198-8859 (Linking)
VI  - 64
IP  - 1
DP  - 2003 Jan
TI  - MHC class II genes in HCV viral clearance of hepatitis C infected Hispanic 
      patients.
PG  - 99-102
AB  - The frequency of class II human leukocyte antigen (HLA) alleles in 112 infected 
      patients of Hispanic ancestry with serology positive for hepatitis C virus (HCV) 
      was investigated. Our studies failed to demonstrate significant association 
      between class II HLA alleles and the outcome of HCV infection: chronic viremia 
      versus spontaneous viral clearance. Our results suggest that the genes 
      responsible for the outcome are unknown, so far, and those HLA associations 
      reported in several ethnic groups may represent genetic markers in nonrandom 
      association with the responsible genes involved in determining viral clearance or 
      chronic viremia following HCV infection.
FAU - Azocar, Jose
AU  - Azocar J
AD  - Northgate Medical, Springfield, MA 02115-6013, USA.
FAU - Clavijo, Olga P
AU  - Clavijo OP
FAU - Yunis, Edmond J
AU  - Yunis EJ
LA  - eng
GR  - HL29583/HL/NHLBI NIH HHS/United States
GR  - HL59838/HL/NHLBI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Hum Immunol
JT  - Human immunology
JID - 8010936
RN  - 0 (HLA-DR Antigens)
SB  - IM
MH  - Adult
MH  - Alleles
MH  - Female
MH  - Genes, MHC Class II/*physiology
MH  - HLA-DR Antigens/genetics
MH  - Hepacivirus/*immunology
MH  - Hepatitis C/*genetics/immunology/transmission
MH  - Hispanic or Latino
MH  - Humans
MH  - Male
MH  - Viremia/*genetics/immunology
EDAT- 2003/01/01 04:00
MHDA- 2004/01/07 05:00
CRDT- 2003/01/01 04:00
PHST- 2003/01/01 04:00 [pubmed]
PHST- 2004/01/07 05:00 [medline]
PHST- 2003/01/01 04:00 [entrez]
AID - S019888590200722X [pii]
AID - 10.1016/s0198-8859(02)00722-x [doi]
PST - ppublish
SO  - Hum Immunol. 2003 Jan;64(1):99-102. doi: 10.1016/s0198-8859(02)00722-x.