PMID- 12510355
OWN - NLM
STAT- MEDLINE
DCOM- 20030220
LR  - 20110727
IS  - 0047-1852 (Print)
IS  - 0047-1852 (Linking)
VI  - 60
IP  - 12
DP  - 2002 Dec
TI  - [New strategies for BMT].
PG  - 2310-7
AB  - Using various autoimmune-prone mice, we have previously shown that conventional 
      allo BMT can be used to treat a range of autoimmune diseases. These findings have 
      recently been confirmed even in humans. However, in humans, the success rate of 
      BMT across major histocompatibility complex(MHC) barriers is lowered by 
      graft-versus-host disease(GvHD), graft rejection, and incomplete T-cell recovery. 
      We have just established a new BMT method in which bone marrow cells(BMCs) are 
      directly injected into the intra-bone marrow(IBM-BMT). We here show that 
      'IBM-BMT' is the best strategy for allo BMT and also organ allografts to induce 
      persistent tolerance.
FAU - Ikehara, Susumu
AU  - Ikehara S
AD  - First Department of Pathology, Transplantation Center, Regeneration Research 
      Center for Intractable Diseases, Kansai Medical University.
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PT  - Review
PL  - Japan
TA  - Nihon Rinsho
JT  - Nihon rinsho. Japanese journal of clinical medicine
JID - 0420546
SB  - IM
MH  - Animals
MH  - Autoimmune Diseases/therapy
MH  - Bone Marrow/pathology
MH  - *Bone Marrow Transplantation/methods/mortality/pathology
MH  - Humans
MH  - Lupus Nephritis/therapy
MH  - Mice
MH  - Tissue Donors
RF  - 18
EDAT- 2003/01/04 04:00
MHDA- 2003/02/21 04:00
CRDT- 2003/01/04 04:00
PHST- 2003/01/04 04:00 [pubmed]
PHST- 2003/02/21 04:00 [medline]
PHST- 2003/01/04 04:00 [entrez]
PST - ppublish
SO  - Nihon Rinsho. 2002 Dec;60(12):2310-7.