PMID- 12512552 OWN - NLM STAT- MEDLINE DCOM- 20030516 LR - 20061115 IS - 1505-1773 (Print) IS - 1505-1773 (Linking) VI - 5 IP - 4 DP - 2002 TI - Antioxidant parameters of horses according to age, sex, breed and environment. PG - 209-16 AB - Antioxidant defences interact to form an integrated system. There is no comprehensive and uniform view on issues concerning the antioxidant status in horses. Therefore, the aim of the present study was to estimate antioxidant parameters in horses of different age, sex and breed as well as environment and relationship between different antioxidants. Parameters of selected antioxidants including superoxide dismutase (SOD), glutathione peroxidase (GSH-px), total antioxidant status (TAS), ceruloplasmin (CP), bilirubin, uric acid, zinc, copper and selenium were determined in blood of 80 clinically healthy horses. Antioxidant parameters significantly varied between horses form different environments or different breed and sex. Age of horses had no significant effect on antioxidant parameters. Significant correlation coefficients were observed between enzymatic and nonenzimatic antioxidants. The nature of the relationship between the antioxidant system in horses with respect to environmental factors is rather complex and to date only a part of system is known. FAU - Gorecka, R AU - Gorecka R AD - Department of Clinical Sciences, Faculty of Veterinary Medicine, Warsaw Agricultural University, Grochowska 272, 03-849 Warsaw, Poland. gorecka@amaltea.sggw.waw.pl FAU - Sitarska, E AU - Sitarska E FAU - Klucinski, W AU - Klucinski W LA - eng PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Germany TA - Pol J Vet Sci JT - Polish journal of veterinary sciences JID - 101125473 RN - 0 (Antioxidants) RN - EC 1.11.1.9 (Glutathione Peroxidase) RN - EC 1.15.1.1 (Superoxide Dismutase) RN - EC 1.16.3.1 (Ceruloplasmin) SB - IM MH - Aging/*metabolism MH - *Animal Husbandry MH - Animals MH - Antioxidants/*metabolism MH - Blood Chemical Analysis/veterinary MH - Ceruloplasmin/genetics/metabolism MH - *Environment MH - Female MH - Glutathione Peroxidase/blood/genetics/metabolism MH - Horses/*classification/*metabolism MH - Male MH - *Sex Characteristics MH - Superoxide Dismutase/blood/genetics/metabolism EDAT- 2003/01/07 04:00 MHDA- 2003/05/17 05:00 CRDT- 2003/01/07 04:00 PHST- 2003/01/07 04:00 [pubmed] PHST- 2003/05/17 05:00 [medline] PHST- 2003/01/07 04:00 [entrez] PST - ppublish SO - Pol J Vet Sci. 2002;5(4):209-16.