PMID- 12518332 OWN - NLM STAT- MEDLINE DCOM- 20030624 LR - 20141120 IS - 0260-437X (Print) IS - 0260-437X (Linking) VI - 23 IP - 1 DP - 2003 Jan-Feb TI - Effect of single and binary combinations of plant-derived molluscicides on different enzyme activities in the nervous tissue of Achatina fulica. PG - 19-22 AB - Effect of single and binary treatments of plant-derived molluscicides on different enzymes--acetylcholinesterase (AChE), lactic dehydrogenase (LDH) and acid/alkaline phosphatase (ACP/ALP)--in the nervous tissue of the harmful terrestrial snail Achatina fulica were studied. Sublethal in vivo 24-h exposure to 40% and 80% LC(50) of Azadirachta indica oil, Cedrus deodara oil, Allium sativum bulb powder, Nerium indicum bark powder and binary combinations of A. sativum (AS) + C. deodara (CD) and CD + A. indica (AI) oils significantly altered the activity of these enzymes in the nervous tissue of Achatina fulica. The binary treatment of AS + CD was more effective against AChE, LDH, and ALP than the single ones. However, binary treatment of AI + CD was more effective against ALP. CI - Copyright 2003 John Wiley & Sons, Ltd. FAU - Rao, I G AU - Rao IG AD - Department of Zoology, DDU Gorakhpur University, Gorakhpur, India. FAU - Singh, Amrita AU - Singh A FAU - Singh, V K AU - Singh VK FAU - Singh, D K AU - Singh DK LA - eng PT - Journal Article PL - England TA - J Appl Toxicol JT - Journal of applied toxicology : JAT JID - 8109495 RN - 0 (Drug Combinations) RN - 0 (Enzyme Inhibitors) RN - 0 (Enzymes) RN - 0 (Molluscacides) RN - 0 (Plant Extracts) RN - EC 1.1.1.27 (L-Lactate Dehydrogenase) RN - EC 3.1.1.7 (Acetylcholinesterase) RN - EC 3.1.3.1 (Alkaline Phosphatase) RN - EC 3.1.3.2 (Acid Phosphatase) SB - IM MH - Acetylcholinesterase/metabolism MH - Acid Phosphatase/metabolism MH - Alkaline Phosphatase/metabolism MH - Animals MH - Dose-Response Relationship, Drug MH - Drug Combinations MH - Enzyme Inhibitors/*pharmacology MH - Enzymes/*metabolism MH - Ganglia, Invertebrate/*drug effects/enzymology MH - In Vitro Techniques MH - L-Lactate Dehydrogenase/metabolism MH - Molluscacides/*pharmacology MH - Plant Extracts/*pharmacology MH - Snails/*enzymology EDAT- 2003/01/09 04:00 MHDA- 2003/06/25 05:00 CRDT- 2003/01/09 04:00 PHST- 2003/01/09 04:00 [pubmed] PHST- 2003/06/25 05:00 [medline] PHST- 2003/01/09 04:00 [entrez] AID - 10.1002/jat.874 [doi] PST - ppublish SO - J Appl Toxicol. 2003 Jan-Feb;23(1):19-22. doi: 10.1002/jat.874.