PMID- 12524558
OWN - NLM
STAT- MEDLINE
DCOM- 20030227
LR  - 20051116
IS  - 0271-8235 (Print)
IS  - 0271-8235 (Linking)
VI  - 22
IP  - 2
DP  - 2002 Jun
TI  - Infectious myelopathies.
PG  - 133-42
AB  - Although infectious myelopathies are rare, timely and accurate diagnosis is 
      essential to improving outcome. There are a number of organisms that may cause 
      infectious myelopathies, including human immunodeficiency virus (HIV), human 
      T-cell lymphotropic virus type I (HTLV-I), herpesviruses, enteroviruses, 
      Treponema pallidum, Mycobacterium tuberculosis, fungi, and parasites. Vacuolar 
      myelopathy, the most common form of spinal cord disease in HIV-infected 
      individuals, is underrecognized clinically. The failure to diagnose this 
      condition is generally a consequence of the attribution of the lower extremity 
      weakness and paresthesias to general debility and concomitant peripheral 
      neuropathy. Tropical spastic paraparesis or HTLV-I-associated myelopathy involves 
      the pyramidal tracts, chiefly at the thoracic level, and results in spastic lower 
      extremity weakness and a spastic bladder. The herpesviruses (varicella-zoster, 
      herpes simplex type 2, cytomegalovirus) and the enteroviruses cause myelitis. 
      Prior to the development of antibiotics, syphilis was the most frequent 
      infectious cause of spinal cord disease. In light of the broad spectrum of 
      pathogens that may affect the spinal cord and the variegate fashion in which 
      these disorders may present, the physician must always consider an infectious 
      etiology in the differential diagnosis for the patient presenting with 
      myelopathy. This review addresses the infectious myelopathies by microorganism.
FAU - Berger, Joseph R
AU  - Berger JR
AD  - Department of Neurology, University of Kentucky College of Medicine, Lexington 
      40536, USA.
FAU - Sabet, Arman
AU  - Sabet A
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Semin Neurol
JT  - Seminars in neurology
JID - 8111343
SB  - IM
MH  - Central Nervous System Fungal Infections/complications
MH  - Central Nervous System Parasitic Infections/complications
MH  - Enterovirus Infections/complications
MH  - Epidural Abscess/etiology/pathology
MH  - Female
MH  - HIV Infections/complications
MH  - HTLV-I Infections/complications
MH  - Herpesviridae Infections/complications
MH  - Humans
MH  - Spinal Cord Diseases/*diagnosis/*microbiology
MH  - Tabes Dorsalis/pathology
MH  - Tuberculosis, Spinal/complications
RF  - 76
EDAT- 2003/01/14 04:00
MHDA- 2003/02/28 04:00
CRDT- 2003/01/14 04:00
PHST- 2003/01/14 04:00 [pubmed]
PHST- 2003/02/28 04:00 [medline]
PHST- 2003/01/14 04:00 [entrez]
AID - 10.1055/s-2002-36536 [doi]
PST - ppublish
SO  - Semin Neurol. 2002 Jun;22(2):133-42. doi: 10.1055/s-2002-36536.